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Total Number of Holdings (excluding cash): 87
| Moderna, Inc. |
MRNA |
60770K107 |
Pharmaceuticals and Biotechnology |
268,319 |
$41,538,464.39 |
2.89% |
| Biogen Inc. |
BIIB |
09062X103 |
Pharmaceuticals and Biotechnology |
114,480 |
$31,239,302.40 |
2.17% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals and Biotechnology |
184,672 |
$30,873,464.96 |
2.14% |
| Boston Scientific Corporation |
BSX |
101137107 |
Medical Equipment and Services |
779,730 |
$30,237,929.40 |
2.10% |
| HCA Healthcare, Inc. |
HCA |
40412C101 |
Health Care Providers |
170,444 |
$29,321,481.32 |
2.04% |
| Cigna Corporation |
CI |
125523100 |
Health Care Providers |
134,649 |
$28,262,825.10 |
1.96% |
| Bio-Rad Laboratories, Inc. (Class A) |
BIO |
090572207 |
Medical Equipment and Services |
48,086 |
$28,106,267.00 |
1.95% |
| Horizon Therapeutics Plc |
HZNP |
G46188101 |
Pharmaceuticals and Biotechnology |
306,562 |
$27,869,551.42 |
1.94% |
| Avantor, Inc. |
AVTR |
05352A100 |
Pharmaceuticals and Biotechnology |
995,785 |
$27,752,527.95 |
1.93% |
| Alexion Pharmaceuticals, Inc. |
ALXN |
015351109 |
Pharmaceuticals and Biotechnology |
179,412 |
$27,405,183.00 |
1.90% |
| Quest Diagnostics Incorporated |
DGX |
74834L100 |
Medical Equipment and Services |
235,222 |
$27,189,310.98 |
1.89% |
| Premier, Inc. (Class A) |
PINC |
74051N102 |
Health Care Providers |
798,613 |
$27,009,091.66 |
1.88% |
| Royalty Pharma Plc- Cl A |
RPRX |
G7709Q104 |
Pharmaceuticals and Biotechnology |
560,067 |
$26,082,320.19 |
1.81% |
| Humana Inc. |
HUM |
444859102 |
Health Care Providers |
68,324 |
$25,939,206.60 |
1.80% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Pharmaceuticals and Biotechnology |
89,750 |
$25,681,065.00 |
1.78% |
| Guardant Health, Inc. |
GH |
40131M109 |
Pharmaceuticals and Biotechnology |
174,000 |
$25,609,320.00 |
1.78% |
| Universal Health Services, Inc. (Class B) |
UHS |
913903100 |
Health Care Providers |
203,865 |
$25,550,400.45 |
1.77% |
| Repligen Corporation |
RGEN |
759916109 |
Medical Equipment and Services |
117,022 |
$24,854,302.58 |
1.73% |
| DaVita Inc. |
DVA |
23918K108 |
Health Care Providers |
238,767 |
$24,385,273.71 |
1.69% |
| NovoCure Limited |
NVCR |
G6674U108 |
Medical Equipment and Services |
161,994 |
$24,153,305.40 |
1.68% |
| Align Technology, Inc. |
ALGN |
016255101 |
Medical Equipment and Services |
41,964 |
$23,798,204.04 |
1.65% |
| IDEXX Laboratories, Inc. |
IDXX |
45168D104 |
Medical Equipment and Services |
44,862 |
$23,335,866.54 |
1.62% |
| Exact Sciences Corporation |
EXAS |
30063P105 |
Pharmaceuticals and Biotechnology |
169,258 |
$23,039,398.96 |
1.60% |
| Molina Healthcare, Inc. |
MOH |
60855R100 |
Health Care Providers |
105,441 |
$22,855,391.16 |
1.59% |
| Hologic, Inc. |
HOLX |
436440101 |
Medical Equipment and Services |
307,909 |
$22,197,159.81 |
1.54% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals and Biotechnology |
1,495,801 |
$22,212,644.85 |
1.54% |
| Sage Therapeutics, Inc. |
SAGE |
78667J108 |
Pharmaceuticals and Biotechnology |
259,219 |
$22,033,615.00 |
1.53% |
| Centene Corporation |
CNC |
15135B101 |
Health Care Providers |
373,564 |
$21,868,436.56 |
1.52% |
| Encompass Health Corporation |
EHC |
29261A100 |
Health Care Providers |
271,195 |
$21,814,925.80 |
1.52% |
| Anthem, Inc. |
ANTM |
036752103 |
Health Care Providers |
69,842 |
$21,175,395.98 |
1.47% |
| Henry Schein, Inc. |
HSIC |
806407102 |
Medical Equipment and Services |
335,403 |
$20,744,675.55 |
1.44% |
| 10X Genomics, Inc. (Class A) |
TXG |
88025U109 |
Medical Equipment and Services |
112,178 |
$19,966,562.22 |
1.39% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals and Biotechnology |
255,731 |
$19,801,251.33 |
1.38% |
| PerkinElmer, Inc. |
PKI |
714046109 |
Medical Equipment and Services |
156,272 |
$19,704,336.48 |
1.37% |
| Amedisys, Inc. |
AMED |
023436108 |
Health Care Providers |
76,449 |
$19,390,524.36 |
1.35% |
| Laboratory Corporation of America Holdings |
LH |
50540R409 |
Medical Equipment and Services |
78,036 |
$18,721,616.76 |
1.30% |
| PRA Health Sciences, Inc. |
PRAH |
69354M108 |
Pharmaceuticals and Biotechnology |
126,629 |
$18,666,380.89 |
1.30% |
| Syneos Health, Inc. |
SYNH |
87166B102 |
Pharmaceuticals and Biotechnology |
233,148 |
$18,033,997.80 |
1.25% |
| Bruker Corporation |
BRKR |
116794108 |
Medical Equipment and Services |
293,449 |
$17,894,520.02 |
1.24% |
| Acadia Healthcare Company, Inc. |
ACHC |
00404A109 |
Health Care Providers |
316,045 |
$17,458,325.80 |
1.21% |
| Hill-Rom Holdings, Inc. |
HRC |
431475102 |
Medical Equipment and Services |
162,135 |
$17,294,940.45 |
1.20% |
| Acceleron Pharma Inc. |
XLRN |
00434H108 |
Pharmaceuticals and Biotechnology |
124,155 |
$16,904,944.80 |
1.17% |
| Agilent Technologies, Inc. |
A |
00846U101 |
Medical Equipment and Services |
134,057 |
$16,364,337.99 |
1.14% |
| Insulet Corporation |
PODD |
45784P101 |
Medical Equipment and Services |
62,139 |
$16,100,214.90 |
1.12% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals and Biotechnology |
96,239 |
$16,172,001.56 |
1.12% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals and Biotechnology |
148,244 |
$15,971,808.56 |
1.11% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals and Biotechnology |
100,930 |
$15,993,367.80 |
1.11% |
| Adaptive Biotechnologies Corporation |
ADPT |
00650F109 |
Pharmaceuticals and Biotechnology |
268,635 |
$15,196,681.95 |
1.06% |
| UnitedHealth Group Incorporated |
UNH |
91324P102 |
Health Care Providers |
45,297 |
$15,048,569.34 |
1.05% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals and Biotechnology |
355,197 |
$14,335,750.92 |
1.00% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals and Biotechnology |
431,524 |
$14,451,738.76 |
1.00% |
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals and Biotechnology |
194,185 |
$14,101,714.70 |
0.98% |
| Bio-Techne Corporation |
TECH |
09073M104 |
Medical Equipment and Services |
35,309 |
$12,770,912.21 |
0.89% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Pharmaceuticals and Biotechnology |
558,670 |
$12,100,792.20 |
0.84% |
| IQVIA Holdings Inc. |
IQV |
46266C105 |
Health Care Providers |
62,580 |
$12,064,798.20 |
0.84% |
| ABIOMED, Inc. |
ABMD |
003654100 |
Medical Equipment and Services |
34,586 |
$11,224,886.30 |
0.78% |
| Medtronic Plc |
MDT |
G5960L103 |
Medical Equipment and Services |
95,722 |
$11,196,602.34 |
0.78% |
| Stryker Corporation |
SYK |
863667101 |
Medical Equipment and Services |
45,757 |
$11,104,766.33 |
0.77% |
| West Pharmaceutical Services, Inc. |
WST |
955306105 |
Medical Equipment and Services |
39,577 |
$11,107,285.05 |
0.77% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals and Biotechnology |
209,345 |
$10,785,454.40 |
0.75% |
| ICU Medical, Inc. |
ICUI |
44930G107 |
Medical Equipment and Services |
52,275 |
$10,847,062.50 |
0.75% |
| Thermo Fisher Scientific Inc. |
TMO |
883556102 |
Medical Equipment and Services |
24,072 |
$10,834,325.76 |
0.75% |
| Masimo Corporation |
MASI |
574795100 |
Medical Equipment and Services |
41,778 |
$10,474,997.94 |
0.73% |
| Steris Plc |
STE |
G8473T100 |
Medical Equipment and Services |
59,158 |
$10,340,818.40 |
0.72% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Pharmaceuticals and Biotechnology |
209,738 |
$10,270,869.86 |
0.71% |
| ResMed Inc. |
RMD |
761152107 |
Medical Equipment and Services |
52,751 |
$10,169,337.78 |
0.71% |
| Intuitive Surgical, Inc. |
ISRG |
46120E602 |
Medical Equipment and Services |
13,705 |
$10,097,844.00 |
0.70% |
| Chemed Corporation |
CHE |
16359R103 |
Health Care Providers |
21,052 |
$9,372,560.92 |
0.65% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals and Biotechnology |
31,359 |
$6,425,145.51 |
0.45% |
| Teladoc Health, Inc. |
TDOC |
87918A105 |
Health Care Providers |
26,479 |
$5,854,242.11 |
0.41% |
| Abbott Laboratories |
ABT |
002824100 |
Pharmaceuticals and Biotechnology |
48,359 |
$5,792,441.02 |
0.40% |
| Catalent, Inc. |
CTLT |
148806102 |
Pharmaceuticals and Biotechnology |
50,878 |
$5,785,337.38 |
0.40% |
| Sarepta Therapeutics, Inc. |
SRPT |
803607100 |
Pharmaceuticals and Biotechnology |
65,766 |
$5,725,587.96 |
0.40% |
| Haemonetics Corporation |
HAE |
405024100 |
Medical Equipment and Services |
44,588 |
$5,640,382.00 |
0.39% |
| The Cooper Companies, Inc. |
COO |
216648402 |
Medical Equipment and Services |
14,574 |
$5,627,458.62 |
0.39% |
| Veeva Systems Inc. (Class A) |
VEEV |
922475108 |
Health Care Providers |
19,449 |
$5,447,859.39 |
0.38% |
| Varian Medical Systems, Inc. |
VAR |
92220P105 |
Medical Equipment and Services |
30,253 |
$5,302,443.31 |
0.37% |
| Baxter International Inc. |
BAX |
071813109 |
Medical Equipment and Services |
65,987 |
$5,126,530.03 |
0.36% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals and Biotechnology |
85,359 |
$5,235,067.47 |
0.36% |
| Danaher Corporation |
DHR |
235851102 |
Medical Equipment and Services |
23,835 |
$5,235,834.45 |
0.36% |
| Teleflex Incorporated |
TFX |
879369106 |
Medical Equipment and Services |
12,865 |
$5,121,813.80 |
0.36% |
| Becton, Dickinson and Company |
BDX |
075887109 |
Medical Equipment and Services |
21,160 |
$5,102,734.00 |
0.35% |
| Globus Medical, Inc. (Class A) |
GMED |
379577208 |
Medical Equipment and Services |
81,184 |
$5,074,000.00 |
0.35% |
| QIAGEN N.V. |
QGEN |
N72482123 |
Medical Equipment and Services |
100,185 |
$5,009,250.00 |
0.35% |
| Quidel Corporation |
QDEL |
74838J101 |
Medical Equipment and Services |
29,472 |
$4,841,070.72 |
0.34% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals and Biotechnology |
31,993 |
$4,966,593.32 |
0.34% |
| Edwards Lifesciences Corporation |
EW |
28176E108 |
Medical Equipment and Services |
58,037 |
$4,822,874.70 |
0.33% |
| US Dollar |
$USD |
|
Other |
1,190,489 |
$1,190,488.63 |
0.08% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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