First Trust Health Care AlphaDEX® Fund (FXH)

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Holdings

Holdings of the Fund as of 6/9/2026
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Total Number of Holdings (excluding cash): 75

Security Name	Identifier	CUSIP	Classification	Shares / Quantity	Market Value	Weighting
Humana Inc.	HUM	444859102	Health Care Providers	108,800	$39,513,984.00	4.39%
Organon & Co.	OGN	68622V106	Pharmaceuticals and Biotechnology	2,519,512	$33,761,460.80	3.75%
Elevance Health Inc.	ELV	036752103	Health Care Providers	64,440	$27,350,269.20	3.04%
DaVita Inc.	DVA	23918K108	Health Care Providers	122,746	$24,327,029.74	2.70%
Solventum Corporation	SOLV	83444M101	Medical Equipment and Services	288,895	$23,822,281.70	2.65%
Exelixis, Inc.	EXEL	30161Q104	Pharmaceuticals and Biotechnology	439,842	$23,307,227.58	2.59%
Molina Healthcare, Inc.	MOH	60855R100	Health Care Providers	113,218	$22,990,047.08	2.55%
The Cigna Group	CI	125523100	Health Care Providers	70,721	$20,862,695.00	2.32%
Incyte Corporation	INCY	45337C102	Pharmaceuticals and Biotechnology	200,434	$20,690,801.82	2.30%
Biogen Inc.	BIIB	09062X103	Pharmaceuticals and Biotechnology	102,901	$20,487,589.10	2.28%
Bio-Rad Laboratories, Inc. (Class A)	BIO	090572207	Medical Equipment and Services	67,677	$20,111,574.09	2.23%
Cardinal Health, Inc.	CAH	14149Y108	Pharmaceuticals and Biotechnology	89,276	$18,986,326.92	2.11%
Zimmer Biomet Holdings, Inc.	ZBH	98956P102	Medical Equipment and Services	208,636	$18,700,044.68	2.08%
Globus Medical, Inc. (Class A)	GMED	379577208	Medical Equipment and Services	218,951	$18,067,836.52	2.01%
Chemed Corporation	CHE	16359R103	Health Care Providers	39,953	$17,829,425.78	1.98%
Encompass Health Corporation	EHC	29261A100	Health Care Providers	156,021	$16,255,827.99	1.81%
Universal Health Services, Inc. (Class B)	UHS	913903100	Health Care Providers	105,408	$15,451,758.72	1.72%
Ionis Pharmaceuticals, Inc.	IONS	462222100	Pharmaceuticals and Biotechnology	200,984	$14,989,386.72	1.67%
Merck & Co., Inc.	MRK	58933Y105	Pharmaceuticals and Biotechnology	125,462	$15,005,255.20	1.67%
Regeneron Pharmaceuticals, Inc.	REGN	75886F107	Pharmaceuticals and Biotechnology	24,416	$15,044,650.88	1.67%
HCA Healthcare, Inc.	HCA	40412C101	Health Care Providers	39,863	$14,944,638.70	1.66%
Amgen Inc.	AMGN	031162100	Pharmaceuticals and Biotechnology	42,893	$14,779,426.56	1.64%
Penumbra, Inc.	PEN	70975L107	Medical Equipment and Services	45,960	$14,755,917.60	1.64%
Illumina, Inc.	ILMN	452327109	Pharmaceuticals and Biotechnology	91,829	$14,695,394.87	1.63%
Becton, Dickinson and Company	BDX	075887109	Medical Equipment and Services	95,986	$14,593,711.44	1.62%
QIAGEN N.V.	QGEN	N72482156	Medical Equipment and Services	376,920	$14,228,730.00	1.58%
United Therapeutics Corporation	UTHR	91307C102	Pharmaceuticals and Biotechnology	25,451	$14,077,966.14	1.56%
Pfizer Inc.	PFE	717081103	Pharmaceuticals and Biotechnology	537,460	$13,812,722.00	1.53%
Revvity, Inc.	RVTY	714046109	Medical Equipment and Services	129,196	$13,453,179.48	1.49%
Tenet Healthcare Corporation	THC	88033G407	Health Care Providers	79,974	$13,304,474.64	1.48%
Natera, Inc.	NTRA	632307104	Medical Equipment and Services	56,598	$12,611,166.36	1.40%
Henry Schein, Inc.	HSIC	806407102	Medical Equipment and Services	153,581	$12,291,087.43	1.37%
Quest Diagnostics Incorporated	DGX	74834L100	Medical Equipment and Services	57,755	$11,812,630.15	1.31%
Labcorp Holdings Inc.	LH	504922105	Medical Equipment and Services	42,423	$11,506,814.52	1.28%
UnitedHealth Group Incorporated	UNH	91324P102	Health Care Providers	27,887	$11,517,331.00	1.28%
Steris Plc	STE	G8473T100	Medical Equipment and Services	51,187	$10,896,688.56	1.21%
The Cooper Companies, Inc.	COO	216648501	Medical Equipment and Services	158,307	$10,863,026.34	1.21%
Medtronic Plc	MDT	G5960L103	Medical Equipment and Services	130,628	$10,708,883.44	1.19%
Bristol-Myers Squibb Company	BMY	110122108	Pharmaceuticals and Biotechnology	186,627	$10,540,692.96	1.17%
GE HealthCare Technologies Inc.	GEHC	36266G107	Medical Equipment and Services	159,018	$10,496,778.18	1.17%
Certara, Inc.	CERT	15687V109	Medical Equipment and Services	1,985,773	$10,286,304.14	1.14%
Gilead Sciences, Inc.	GILD	375558103	Pharmaceuticals and Biotechnology	81,215	$10,192,482.50	1.13%
ResMed Inc.	RMD	761152107	Medical Equipment and Services	50,423	$9,930,305.62	1.10%
Neurocrine Biosciences, Inc.	NBIX	64125C109	Pharmaceuticals and Biotechnology	57,279	$9,464,781.96	1.05%
Eli Lilly and Company	LLY	532457108	Pharmaceuticals and Biotechnology	8,204	$9,390,954.72	1.04%
Waters Corporation	WAT	941848103	Medical Equipment and Services	25,339	$9,404,569.85	1.04%
Insmed Incorporated	INSM	457669307	Pharmaceuticals and Biotechnology	92,294	$9,140,797.76	1.02%
Agilent Technologies, Inc.	A	00846U101	Medical Equipment and Services	66,204	$8,969,317.92	1.00%
Halozyme Therapeutics, Inc.	HALO	40637H109	Pharmaceuticals and Biotechnology	116,756	$8,345,718.88	0.93%
IQVIA Holdings Inc.	IQV	46266C105	Health Care Providers	44,247	$8,241,003.75	0.92%
Sarepta Therapeutics, Inc.	SRPT	803607100	Pharmaceuticals and Biotechnology	520,170	$8,265,501.30	0.92%
Align Technology, Inc.	ALGN	016255101	Medical Equipment and Services	44,018	$7,839,605.80	0.87%
BioMarin Pharmaceutical Inc.	BMRN	09061G101	Pharmaceuticals and Biotechnology	133,580	$7,735,617.80	0.86%
Thermo Fisher Scientific Inc.	TMO	883556102	Medical Equipment and Services	15,352	$7,584,962.64	0.84%
Johnson & Johnson	JNJ	478160104	Pharmaceuticals and Biotechnology	30,870	$7,316,190.00	0.81%
Medpace Holdings, Inc.	MEDP	58506Q109	Pharmaceuticals and Biotechnology	15,714	$7,335,138.06	0.81%
Abbott Laboratories	ABT	002824100	Medical Equipment and Services	73,497	$6,706,601.25	0.75%
Medline Inc. (Class A)	MDLN	58507V107	Medical Equipment and Services	169,572	$6,106,287.72	0.68%
Zoetis Inc.	ZTS	98978V103	Pharmaceuticals and Biotechnology	63,835	$5,247,237.00	0.58%
West Pharmaceutical Services, Inc.	WST	955306105	Medical Equipment and Services	14,113	$4,723,056.58	0.52%
DexCom, Inc.	DXCM	252131107	Medical Equipment and Services	56,324	$4,403,973.56	0.49%
Royalty Pharma Plc (Class A)	RPRX	G7709Q104	Pharmaceuticals and Biotechnology	73,737	$4,101,989.31	0.46%
Sotera Health Company	SHC	83601L102	Medical Equipment and Services	246,664	$4,077,355.92	0.45%
Edwards Lifesciences Corporation	EW	28176E108	Medical Equipment and Services	44,170	$3,866,641.80	0.43%
AbbVie Inc.	ABBV	00287Y109	Pharmaceuticals and Biotechnology	16,264	$3,666,230.88	0.41%
IDEXX Laboratories, Inc.	IDXX	45168D104	Medical Equipment and Services	6,295	$3,644,112.55	0.40%
Danaher Corporation	DHR	235851102	Medical Equipment and Services	18,656	$3,514,976.96	0.39%
Vertex Pharmaceuticals Incorporated	VRTX	92532F100	Pharmaceuticals and Biotechnology	7,921	$3,530,944.17	0.39%
Envista Holdings Corporation	NVST	29415F104	Medical Equipment and Services	139,423	$3,428,411.57	0.38%
Stryker Corporation	SYK	863667101	Medical Equipment and Services	10,765	$3,380,317.65	0.38%
Veeva Systems Inc. (Class A)	VEEV	922475108	Health Care Providers	20,136	$3,376,404.48	0.38%
Intuitive Surgical, Inc.	ISRG	46120E602	Medical Equipment and Services	7,673	$3,273,378.53	0.36%
Alnylam Pharmaceuticals, Inc.	ALNY	02043Q107	Pharmaceuticals and Biotechnology	10,690	$3,182,306.10	0.35%
Viking Therapeutics, Inc.	VKTX	92686J106	Pharmaceuticals and Biotechnology	108,702	$3,177,359.46	0.35%
Boston Scientific Corporation	BSX	101137107	Medical Equipment and Services	56,369	$2,759,826.24	0.31%
US Dollar	$USD		Other	1,012,610	$1,012,610.20	0.11%

Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.