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Total Number of Holdings (excluding cash): 85
| Moderna, Inc. |
MRNA |
60770K107 |
Pharmaceuticals and Biotechnology |
130,414 |
$57,476,058.08 |
3.46% |
| Avantor, Inc. |
AVTR |
05352A100 |
Medical Equipment and Services |
862,995 |
$37,971,780.00 |
2.28% |
| Bio-Rad Laboratories, Inc. (Class A) |
BIO |
090572207 |
Medical Equipment and Services |
47,565 |
$37,368,966.60 |
2.25% |
| Quidel Corporation |
QDEL |
74838J101 |
Medical Equipment and Services |
239,189 |
$37,019,281.53 |
2.23% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Pharmaceuticals and Biotechnology |
82,841 |
$36,975,251.94 |
2.22% |
| Quest Diagnostics Incorporated |
DGX |
74834L100 |
Medical Equipment and Services |
232,212 |
$35,461,094.52 |
2.13% |
| Hologic, Inc. |
HOLX |
436440101 |
Medical Equipment and Services |
459,309 |
$35,247,372.66 |
2.12% |
| Premier, Inc. (Class A) |
PINC |
74051N102 |
Health Care Providers |
880,855 |
$34,291,685.15 |
2.06% |
| Novavax, Inc. |
NVAX |
670002401 |
Pharmaceuticals and Biotechnology |
144,342 |
$33,488,787.42 |
2.02% |
| The Cooper Companies, Inc. |
COO |
216648402 |
Medical Equipment and Services |
77,335 |
$33,544,829.60 |
2.02% |
| IQVIA Holdings Inc. |
IQV |
46266C105 |
Health Care Providers |
126,463 |
$32,848,764.25 |
1.98% |
| Laboratory Corporation of America Holdings |
LH |
50540R409 |
Medical Equipment and Services |
111,094 |
$32,379,457.24 |
1.95% |
| PPD, Inc. |
PPD |
69355F102 |
Medical Equipment and Services |
664,897 |
$31,117,179.60 |
1.87% |
| West Pharmaceutical Services, Inc. |
WST |
955306105 |
Medical Equipment and Services |
68,272 |
$30,666,416.96 |
1.85% |
| HCA Healthcare, Inc. |
HCA |
40412C101 |
Health Care Providers |
118,585 |
$30,624,576.25 |
1.84% |
| Universal Health Services, Inc. (Class B) |
UHS |
913903100 |
Health Care Providers |
209,282 |
$30,481,923.30 |
1.83% |
| Danaher Corporation |
DHR |
235851102 |
Medical Equipment and Services |
91,353 |
$29,610,247.89 |
1.78% |
| PerkinElmer, Inc. |
PKI |
714046109 |
Medical Equipment and Services |
158,773 |
$29,380,943.65 |
1.77% |
| Bio-Techne Corporation |
TECH |
09073M104 |
Medical Equipment and Services |
54,450 |
$29,021,850.00 |
1.75% |
| Agilent Technologies, Inc. |
A |
00846U101 |
Medical Equipment and Services |
165,863 |
$28,601,415.72 |
1.72% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Pharmaceuticals and Biotechnology |
43,893 |
$28,401,404.58 |
1.71% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals and Biotechnology |
136,649 |
$27,592,166.08 |
1.66% |
| Bruker Corporation |
BRKR |
116794108 |
Medical Equipment and Services |
322,664 |
$26,919,857.52 |
1.62% |
| Molina Healthcare, Inc. |
MOH |
60855R100 |
Health Care Providers |
96,877 |
$26,856,241.94 |
1.62% |
| Cigna Corporation |
CI |
125523100 |
Health Care Providers |
129,266 |
$26,110,439.34 |
1.57% |
| IDEXX Laboratories, Inc. |
IDXX |
45168D104 |
Medical Equipment and Services |
38,819 |
$26,065,793.93 |
1.57% |
| Syneos Health, Inc. |
SYNH |
87166B102 |
Pharmaceuticals and Biotechnology |
273,953 |
$26,102,241.84 |
1.57% |
| Sage Therapeutics, Inc. |
SAGE |
78667J108 |
Pharmaceuticals and Biotechnology |
539,430 |
$23,923,720.50 |
1.44% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals and Biotechnology |
293,818 |
$23,220,436.54 |
1.40% |
| Humana Inc. |
HUM |
444859102 |
Health Care Providers |
55,375 |
$22,169,381.25 |
1.33% |
| Thermo Fisher Scientific Inc. |
TMO |
883556102 |
Medical Equipment and Services |
36,448 |
$22,110,450.24 |
1.33% |
| Align Technology, Inc. |
ALGN |
016255101 |
Medical Equipment and Services |
30,093 |
$21,564,944.73 |
1.30% |
| Horizon Therapeutics Plc |
HZNP |
G46188101 |
Pharmaceuticals and Biotechnology |
196,358 |
$21,591,525.68 |
1.30% |
| Centene Corporation |
CNC |
15135B101 |
Health Care Providers |
336,159 |
$21,157,847.46 |
1.27% |
| QIAGEN N.V. |
QGEN |
N72482123 |
Medical Equipment and Services |
380,055 |
$20,808,011.25 |
1.25% |
| Natera, Inc. |
NTRA |
632307104 |
Medical Equipment and Services |
161,958 |
$20,354,881.44 |
1.22% |
| 10X Genomics, Inc. (Class A) |
TXG |
88025U109 |
Medical Equipment and Services |
125,198 |
$19,875,182.50 |
1.20% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Pharmaceuticals and Biotechnology |
108,466 |
$19,763,589.86 |
1.19% |
| Henry Schein, Inc. |
HSIC |
806407102 |
Medical Equipment and Services |
247,838 |
$19,048,828.68 |
1.15% |
| Globus Medical, Inc. (Class A) |
GMED |
379577208 |
Medical Equipment and Services |
237,161 |
$18,870,900.77 |
1.14% |
| UnitedHealth Group Incorporated |
UNH |
91324P102 |
Health Care Providers |
45,919 |
$18,767,095.30 |
1.13% |
| Chemed Corporation |
CHE |
16359R103 |
Health Care Providers |
38,752 |
$18,333,571.20 |
1.10% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals and Biotechnology |
80,110 |
$18,289,113.00 |
1.10% |
| Anthem, Inc. |
ANTM |
036752103 |
Health Care Providers |
48,159 |
$18,083,222.91 |
1.09% |
| NovoCure Limited |
NVCR |
G6674U108 |
Pharmaceuticals and Biotechnology |
138,151 |
$18,114,359.12 |
1.09% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals and Biotechnology |
138,010 |
$17,879,195.50 |
1.08% |
| Cerner Corporation |
CERN |
156782104 |
Health Care Providers |
235,246 |
$17,163,548.16 |
1.03% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals and Biotechnology |
1,286,704 |
$17,048,828.00 |
1.03% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals and Biotechnology |
91,193 |
$16,804,134.11 |
1.01% |
| Hill-Rom Holdings, Inc. |
HRC |
431475102 |
Medical Equipment and Services |
107,915 |
$16,278,977.75 |
0.98% |
| Royalty Pharma Plc- Cl A |
RPRX |
G7709Q104 |
Pharmaceuticals and Biotechnology |
448,572 |
$16,278,677.88 |
0.98% |
| Catalent, Inc. |
CTLT |
148806102 |
Pharmaceuticals and Biotechnology |
113,373 |
$15,555,909.33 |
0.94% |
| Biogen Inc. |
BIIB |
09062X103 |
Pharmaceuticals and Biotechnology |
53,101 |
$15,363,181.32 |
0.92% |
| ICU Medical, Inc. |
ICUI |
44930G107 |
Medical Equipment and Services |
59,563 |
$14,225,431.29 |
0.86% |
| ResMed Inc. |
RMD |
761152107 |
Medical Equipment and Services |
49,724 |
$14,344,379.52 |
0.86% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals and Biotechnology |
313,024 |
$13,757,404.80 |
0.83% |
| Abbott Laboratories |
ABT |
002824100 |
Medical Equipment and Services |
105,738 |
$13,180,241.70 |
0.79% |
| Becton, Dickinson and Company |
BDX |
075887109 |
Medical Equipment and Services |
50,403 |
$12,943,490.40 |
0.78% |
| Integra LifeSciences Holdings Corporation |
IART |
457985208 |
Medical Equipment and Services |
179,629 |
$12,777,010.77 |
0.77% |
| Penumbra, Inc. |
PEN |
70975L107 |
Medical Equipment and Services |
44,727 |
$12,813,390.96 |
0.77% |
| DaVita Inc. |
DVA |
23918K108 |
Health Care Providers |
101,787 |
$12,327,423.57 |
0.74% |
| Encompass Health Corporation |
EHC |
29261A100 |
Health Care Providers |
157,095 |
$12,057,041.25 |
0.73% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals and Biotechnology |
74,409 |
$12,197,867.37 |
0.73% |
| Veeva Systems Inc. (Class A) |
VEEV |
922475108 |
Health Care Providers |
39,421 |
$11,725,776.45 |
0.71% |
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals and Biotechnology |
157,621 |
$11,355,016.84 |
0.68% |
| Zimmer Biomet Holdings, Inc. |
ZBH |
98956P102 |
Medical Equipment and Services |
76,224 |
$11,105,836.80 |
0.67% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals and Biotechnology |
214,713 |
$10,952,510.13 |
0.66% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals and Biotechnology |
50,289 |
$10,743,741.96 |
0.65% |
| Repligen Corporation |
RGEN |
759916109 |
Medical Equipment and Services |
28,998 |
$9,079,273.80 |
0.55% |
| DexCom, Inc. |
DXCM |
252131107 |
Medical Equipment and Services |
13,556 |
$7,732,613.52 |
0.47% |
| Edwards Lifesciences Corporation |
EW |
28176E108 |
Medical Equipment and Services |
55,889 |
$6,687,677.74 |
0.40% |
| Masimo Corporation |
MASI |
574795100 |
Medical Equipment and Services |
23,876 |
$6,603,385.32 |
0.40% |
| Intuitive Surgical, Inc. |
ISRG |
46120E602 |
Medical Equipment and Services |
6,295 |
$6,474,218.65 |
0.39% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals and Biotechnology |
31,062 |
$6,254,333.70 |
0.38% |
| Seagen Inc. |
SGEN |
81181C104 |
Pharmaceuticals and Biotechnology |
36,665 |
$6,202,251.40 |
0.37% |
| Acadia Healthcare Company, Inc. |
ACHC |
00404A109 |
Health Care Providers |
92,248 |
$6,042,244.00 |
0.36% |
| Medtronic Plc |
MDT |
G5960L103 |
Medical Equipment and Services |
46,632 |
$6,011,331.12 |
0.36% |
| Steris Plc |
STE |
G8473T100 |
Medical Equipment and Services |
28,057 |
$6,052,175.47 |
0.36% |
| Baxter International Inc. |
BAX |
071813109 |
Medical Equipment and Services |
71,906 |
$5,827,981.30 |
0.35% |
| Envista Holdings Corporation |
NVST |
29415F104 |
Medical Equipment and Services |
133,964 |
$5,599,695.20 |
0.34% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals and Biotechnology |
51,389 |
$5,468,303.49 |
0.33% |
| DENTSPLY SIRONA Inc. |
XRAY |
24906P109 |
Medical Equipment and Services |
91,503 |
$5,466,389.22 |
0.33% |
| Illumina, Inc. |
ILMN |
452327109 |
Pharmaceuticals and Biotechnology |
12,232 |
$5,315,904.88 |
0.32% |
| Incyte Corporation |
INCY |
45337C102 |
Pharmaceuticals and Biotechnology |
68,806 |
$4,788,209.54 |
0.29% |
| Amedisys, Inc. |
AMED |
023436108 |
Health Care Providers |
23,634 |
$3,879,521.10 |
0.23% |
| US Dollar |
$USD |
|
Other |
1,838,467 |
$1,838,467.03 |
0.11% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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