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Total Number of Holdings (excluding cash): 76
| Centene Corporation |
CNC |
Health Care Providers & Services |
660,648 |
$41,898,296.16 |
3.68% |
| DexCom, Inc. |
DXCM |
Health Care Equipment & Supplies |
115,722 |
$27,246,744.90 |
2.39% |
| Envista Holdings Corporation |
NVST |
Health Care Equipment & Supplies |
854,012 |
$27,157,581.60 |
2.39% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
Biotechnology |
219,788 |
$25,721,789.64 |
2.26% |
| Exelixis, Inc. |
EXEL |
Biotechnology |
1,436,601 |
$25,485,301.74 |
2.24% |
| Horizon Therapeutics Plc |
HZNP |
Pharmaceuticals |
699,253 |
$25,194,085.59 |
2.21% |
| Alexion Pharmaceuticals, Inc. |
ALXN |
Biotechnology |
234,054 |
$24,645,886.20 |
2.17% |
| Cigna Corporation |
CI |
Health Care Providers & Services |
123,786 |
$24,751,010.70 |
2.17% |
| Jazz Pharmaceuticals Plc |
JAZZ |
Pharmaceuticals |
169,567 |
$24,476,996.45 |
2.15% |
| Seattle Genetics, Inc. |
SGEN |
Biotechnology |
221,537 |
$24,464,330.91 |
2.15% |
| UnitedHealth Group Incorporated |
UNH |
Health Care Providers & Services |
86,105 |
$24,461,569.45 |
2.15% |
| Biogen Inc. |
BIIB |
Biotechnology |
85,306 |
$23,982,928.84 |
2.11% |
| Humana Inc. |
HUM |
Health Care Providers & Services |
69,062 |
$23,958,298.42 |
2.10% |
| Neurocrine Biosciences, Inc. |
NBIX |
Biotechnology |
235,491 |
$23,231,187.15 |
2.04% |
| Perrigo Company Plc |
PRGO |
Pharmaceuticals |
391,993 |
$22,994,309.38 |
2.02% |
| Insulet Corporation |
PODD |
Health Care Equipment & Supplies |
118,285 |
$22,830,187.85 |
2.01% |
| Chemed Corporation |
CHE |
Health Care Providers & Services |
46,101 |
$22,065,321.63 |
1.94% |
| Mylan N.V. |
MYL |
Pharmaceuticals |
1,007,480 |
$21,318,276.80 |
1.87% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
Biotechnology |
92,488 |
$21,028,996.56 |
1.85% |
| ResMed Inc. |
RMD |
Health Care Equipment & Supplies |
130,672 |
$20,988,536.64 |
1.84% |
| Pfizer Inc. |
PFE |
Pharmaceuticals |
516,854 |
$20,756,856.64 |
1.82% |
| Bruker Corporation |
BRKR |
Life Sciences Tools & Services |
397,299 |
$20,452,952.52 |
1.80% |
| Charles River Laboratories International, Inc. |
CRL |
Life Sciences Tools & Services |
132,563 |
$20,490,262.91 |
1.80% |
| Universal Health Services, Inc. (Class B) |
UHS |
Health Care Providers & Services |
141,156 |
$20,464,796.88 |
1.80% |
| Bristol-Myers Squibb Company |
BMY |
Pharmaceuticals |
315,475 |
$20,095,757.50 |
1.77% |
| Edwards Lifesciences Corporation |
EW |
Health Care Equipment & Supplies |
86,803 |
$19,870,942.76 |
1.75% |
| HCA Healthcare, Inc. |
HCA |
Health Care Providers & Services |
137,003 |
$19,399,624.80 |
1.70% |
| Molina Healthcare, Inc. |
MOH |
Health Care Providers & Services |
149,240 |
$19,169,878.00 |
1.68% |
| Anthem, Inc. |
ANTM |
Health Care Providers & Services |
67,048 |
$19,027,551.92 |
1.67% |
| Encompass Health Corporation |
EHC |
Health Care Providers & Services |
205,551 |
$15,897,314.34 |
1.40% |
| Laboratory Corporation of America Holdings |
LH |
Health Care Providers & Services |
84,167 |
$14,938,800.83 |
1.31% |
| Penumbra, Inc. |
PEN |
Health Care Equipment & Supplies |
86,677 |
$14,946,581.88 |
1.31% |
| West Pharmaceutical Services, Inc. |
WST |
Health Care Equipment & Supplies |
94,715 |
$14,727,235.35 |
1.29% |
| Zoetis Inc. |
ZTS |
Pharmaceuticals |
107,582 |
$14,626,848.72 |
1.29% |
| Quest Diagnostics Incorporated |
DGX |
Health Care Providers & Services |
133,332 |
$14,595,854.04 |
1.28% |
| Varian Medical Systems, Inc. |
VAR |
Health Care Equipment & Supplies |
100,264 |
$14,593,425.20 |
1.28% |
| Thermo Fisher Scientific Inc. |
TMO |
Life Sciences Tools & Services |
43,828 |
$14,505,314.88 |
1.27% |
| Teleflex Incorporated |
TFX |
Health Care Equipment & Supplies |
37,824 |
$14,317,140.48 |
1.26% |
| Guardant Health, Inc. |
GH |
Health Care Providers & Services |
182,219 |
$14,187,571.34 |
1.25% |
| Bio-Techne Corporation |
TECH |
Life Sciences Tools & Services |
64,865 |
$14,062,083.35 |
1.24% |
| Align Technology, Inc. |
ALGN |
Health Care Equipment & Supplies |
51,026 |
$13,313,193.66 |
1.17% |
| Amgen Inc. |
AMGN |
Biotechnology |
59,063 |
$13,168,095.85 |
1.16% |
| PRA Health Sciences, Inc. |
PRAH |
Life Sciences Tools & Services |
128,102 |
$13,229,093.54 |
1.16% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
Biotechnology |
37,921 |
$12,871,145.82 |
1.13% |
| Incyte Corporation |
INCY |
Biotechnology |
163,061 |
$12,404,050.27 |
1.09% |
| DaVita Inc. |
DVA |
Health Care Providers & Services |
134,948 |
$11,069,784.44 |
0.97% |
| McKesson Corporation |
MCK |
Health Care Providers & Services |
73,201 |
$11,026,266.63 |
0.97% |
| Baxter International Inc. |
BAX |
Health Care Equipment & Supplies |
121,086 |
$10,961,915.58 |
0.96% |
| Eli Lilly and Company |
LLY |
Pharmaceuticals |
77,039 |
$10,655,264.09 |
0.94% |
| Masimo Corporation |
MASI |
Health Care Equipment & Supplies |
64,059 |
$10,743,975.48 |
0.94% |
| Danaher Corporation |
DHR |
Health Care Equipment & Supplies |
65,971 |
$10,634,525.20 |
0.93% |
| AmerisourceBergen Corporation |
ABC |
Health Care Providers & Services |
119,091 |
$10,422,844.32 |
0.92% |
| Agilent Technologies, Inc. |
A |
Life Sciences Tools & Services |
118,687 |
$10,273,546.72 |
0.90% |
| PerkinElmer, Inc. |
PKI |
Life Sciences Tools & Services |
104,275 |
$10,288,814.25 |
0.90% |
| Bio-Rad Laboratories, Inc. (Class A) |
BIO |
Life Sciences Tools & Services |
27,363 |
$9,996,798.42 |
0.88% |
| Steris Plc |
STE |
Health Care Equipment & Supplies |
66,429 |
$9,971,657.19 |
0.88% |
| Intuitive Surgical, Inc. |
ISRG |
Health Care Equipment & Supplies |
17,128 |
$9,720,140.00 |
0.85% |
| AbbVie Inc. |
ABBV |
Biotechnology |
114,357 |
$9,608,275.14 |
0.84% |
| Hill-Rom Holdings, Inc. |
HRC |
Health Care Equipment & Supplies |
89,185 |
$9,525,849.85 |
0.84% |
| Merck & Co., Inc. |
MRK |
Pharmaceuticals |
111,326 |
$9,585,168.60 |
0.84% |
| Moderna, Inc. |
MRNA |
Biotechnology |
242,647 |
$5,517,792.78 |
0.48% |
| Agios Pharmaceuticals, Inc. |
AGIO |
Biotechnology |
99,396 |
$5,237,175.24 |
0.46% |
| The Cooper Companies, Inc. |
COO |
Health Care Equipment & Supplies |
14,772 |
$5,232,390.12 |
0.46% |
| Medtronic Plc |
MDT |
Health Care Equipment & Supplies |
41,834 |
$4,987,867.82 |
0.44% |
| Becton, Dickinson and Company |
BDX |
Health Care Equipment & Supplies |
17,451 |
$4,881,917.25 |
0.43% |
| Hologic, Inc. |
HOLX |
Health Care Equipment & Supplies |
90,905 |
$4,883,416.60 |
0.43% |
| Johnson & Johnson |
JNJ |
Pharmaceuticals |
32,537 |
$4,839,878.75 |
0.43% |
| Stryker Corporation |
SYK |
Health Care Equipment & Supplies |
22,608 |
$4,851,676.80 |
0.43% |
| Cerner Corporation |
CERN |
Health Care Technology |
64,671 |
$4,747,498.11 |
0.42% |
| IQVIA Holdings Inc. |
IQV |
Life Sciences Tools & Services |
30,718 |
$4,827,640.88 |
0.42% |
| Gilead Sciences, Inc. |
GILD |
Biotechnology |
73,040 |
$4,662,143.20 |
0.41% |
| ICU Medical, Inc. |
ICUI |
Health Care Equipment & Supplies |
25,364 |
$4,717,704.00 |
0.41% |
| Exact Sciences Corporation |
EXAS |
Biotechnology |
51,321 |
$4,512,655.53 |
0.40% |
| Boston Scientific Corporation |
BSX |
Health Care Equipment & Supplies |
104,958 |
$4,476,458.70 |
0.39% |
| Premier, Inc. (Class A) |
PINC |
Health Care Providers & Services |
125,295 |
$4,430,431.20 |
0.39% |
| Sarepta Therapeutics, Inc. |
SRPT |
Biotechnology |
36,780 |
$4,105,383.60 |
0.36% |
| US Dollar |
$USD |
Other |
2,765,061 |
$2,765,060.56 |
0.24% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial advisors are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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