First Trust Health Care AlphaDEX® Fund (FXH)

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Holdings

Holdings of the Fund as of 7/22/2026
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Total Number of Holdings (excluding cash): 73

Security Name	Identifier	CUSIP	Classification	Shares / Quantity	Market Value	Weighting
Regeneron Pharmaceuticals, Inc.	REGN	75886F107	Pharmaceuticals and Biotechnology	37,598	$24,483,065.64	2.47%
DaVita Inc.	DVA	23918K108	Health Care Providers	105,371	$24,454,501.68	2.46%
The Cigna Group	CI	125523100	Health Care Providers	85,039	$24,223,359.15	2.44%
Pfizer Inc.	PFE	717081103	Pharmaceuticals and Biotechnology	973,556	$24,163,659.92	2.43%
Zimmer Biomet Holdings, Inc.	ZBH	98956P102	Medical Equipment and Services	272,312	$24,148,628.16	2.43%
Centene Corporation	CNC	15135B101	Health Care Providers	365,217	$24,064,148.13	2.42%
Boston Scientific Corporation	BSX	101137107	Medical Equipment and Services	549,279	$23,602,518.63	2.38%
Solventum Corporation	SOLV	83444M101	Medical Equipment and Services	303,865	$23,592,078.60	2.38%
Guardant Health, Inc.	GH	40131M109	Pharmaceuticals and Biotechnology	156,258	$23,555,893.50	2.37%
Universal Health Services, Inc. (Class B)	UHS	913903100	Health Care Providers	157,664	$23,545,541.76	2.37%
Axsome Therapeutics, Inc.	AXSM	05464T104	Pharmaceuticals and Biotechnology	95,778	$22,950,324.36	2.31%
Natera, Inc.	NTRA	632307104	Medical Equipment and Services	86,364	$22,819,096.08	2.30%
Globus Medical, Inc. (Class A)	GMED	379577208	Medical Equipment and Services	296,711	$22,401,680.50	2.26%
Medline Inc. (Class A)	MDLN	58507V107	Medical Equipment and Services	594,403	$22,099,903.54	2.23%
Encompass Health Corporation	EHC	29261A100	Health Care Providers	173,171	$19,225,444.42	1.94%
Arrowhead Pharmaceuticals, Inc.	ARWR	04280A100	Pharmaceuticals and Biotechnology	214,749	$19,048,236.30	1.92%
Medtronic Plc	MDT	G5960L103	Medical Equipment and Services	223,755	$18,323,296.95	1.85%
Corcept Therapeutics Inc.	CORT	218352102	Pharmaceuticals and Biotechnology	201,314	$18,295,416.32	1.84%
Tenet Healthcare Corporation	THC	88033G407	Health Care Providers	93,566	$18,278,118.10	1.84%
QIAGEN N.V.	QGEN	N72482156	Pharmaceuticals and Biotechnology	447,678	$18,162,296.47	1.83%
Zoetis Inc.	ZTS	98978V103	Pharmaceuticals and Biotechnology	243,587	$18,071,719.53	1.82%
Neurocrine Biosciences, Inc.	NBIX	64125C109	Pharmaceuticals and Biotechnology	103,861	$17,935,756.09	1.81%
Incyte Corporation	INCY	45337C102	Pharmaceuticals and Biotechnology	154,412	$17,879,365.48	1.80%
Elevance Health Inc.	ELV	036752103	Health Care Providers	45,263	$17,611,380.67	1.77%
Halozyme Therapeutics, Inc.	HALO	40637H109	Pharmaceuticals and Biotechnology	223,640	$17,403,664.80	1.75%
ResMed Inc.	RMD	761152107	Medical Equipment and Services	89,821	$17,327,369.11	1.75%
United Therapeutics Corporation	UTHR	91307C102	Pharmaceuticals and Biotechnology	32,305	$17,026,996.35	1.72%
Eli Lilly and Company	LLY	532457108	Pharmaceuticals and Biotechnology	14,595	$16,974,130.95	1.71%
Ascendis Pharma A/S	ASND	K08588103	Pharmaceuticals and Biotechnology	65,629	$16,533,913.97	1.67%
Viatris Inc.	VTRS	92556V106	Pharmaceuticals and Biotechnology	885,763	$15,066,828.63	1.52%
Bristol-Myers Squibb Company	BMY	110122108	Pharmaceuticals and Biotechnology	244,116	$14,832,488.16	1.49%
Gilead Sciences, Inc.	GILD	375558103	Pharmaceuticals and Biotechnology	111,334	$14,511,273.56	1.46%
Becton, Dickinson and Company	BDX	075887109	Medical Equipment and Services	92,948	$14,235,915.68	1.43%
Exelixis, Inc.	EXEL	30161Q104	Pharmaceuticals and Biotechnology	258,517	$14,213,264.66	1.43%
Labcorp Holdings Inc.	LH	504922105	Medical Equipment and Services	50,235	$14,139,143.10	1.42%
Steris Plc	STE	G8473T100	Medical Equipment and Services	66,800	$14,066,076.00	1.42%
Medpace Holdings, Inc.	MEDP	58506Q109	Pharmaceuticals and Biotechnology	26,560	$14,026,867.20	1.41%
Doximity, Inc. (Class A)	DOCS	26622P107	Health Care Providers	678,204	$13,896,399.96	1.40%
Quest Diagnostics Incorporated	DGX	74834L100	Medical Equipment and Services	66,364	$13,925,158.12	1.40%
Revolution Medicines, Inc.	RVMD	76155X100	Pharmaceuticals and Biotechnology	75,107	$13,746,834.21	1.39%
GE HealthCare Technologies Inc.	GEHC	36266G107	Medical Equipment and Services	219,746	$13,494,601.86	1.36%
Biogen Inc.	BIIB	09062X103	Pharmaceuticals and Biotechnology	65,101	$12,873,071.74	1.30%
Abbott Laboratories	ABT	002824100	Medical Equipment and Services	96,454	$9,700,378.78	0.98%
BridgeBio Pharma, Inc.	BBIO	10806X102	Pharmaceuticals and Biotechnology	117,510	$9,713,376.60	0.98%
Ionis Pharmaceuticals, Inc.	IONS	462222100	Pharmaceuticals and Biotechnology	177,398	$9,581,265.98	0.97%
Chemed Corporation	CHE	16359R103	Health Care Providers	18,791	$9,461,644.32	0.95%
Thermo Fisher Scientific Inc.	TMO	883556102	Medical Equipment and Services	17,457	$9,190,412.22	0.93%
Veeva Systems Inc. (Class A)	VEEV	922475108	Health Care Providers	49,317	$9,101,452.35	0.92%
IQVIA Holdings Inc.	IQV	46266C105	Health Care Providers	45,297	$8,992,360.44	0.91%
Align Technology, Inc.	ALGN	016255101	Medical Equipment and Services	51,891	$8,949,121.86	0.90%
Henry Schein, Inc.	HSIC	806407102	Medical Equipment and Services	104,791	$8,887,324.71	0.90%
AbbVie Inc.	ABBV	00287Y109	Pharmaceuticals and Biotechnology	34,779	$8,809,520.70	0.89%
Agilent Technologies, Inc.	A	00846U101	Medical Equipment and Services	65,889	$8,793,545.94	0.89%
Madrigal Pharmaceuticals, Inc.	MDGL	558868105	Pharmaceuticals and Biotechnology	16,300	$8,763,695.00	0.88%
Organon & Co.	OGN	68622V106	Pharmaceuticals and Biotechnology	646,392	$8,739,219.84	0.88%
HCA Healthcare, Inc.	HCA	40412C101	Health Care Providers	22,449	$8,348,109.63	0.84%
Vertex Pharmaceuticals Incorporated	VRTX	92532F100	Pharmaceuticals and Biotechnology	17,619	$8,326,210.83	0.84%
Tempus AI, Inc. (Class A)	TEM	88023B103	Pharmaceuticals and Biotechnology	151,082	$7,094,810.72	0.71%
Illumina, Inc.	ILMN	452327109	Pharmaceuticals and Biotechnology	24,889	$4,750,563.43	0.48%
DexCom, Inc.	DXCM	252131107	Medical Equipment and Services	64,976	$4,641,235.68	0.47%
The Ensign Group, Inc.	ENSG	29358P101	Health Care Providers	27,298	$4,616,364.78	0.47%
Bio-Rad Laboratories, Inc. (Class A)	BIO	090572207	Medical Equipment and Services	14,903	$4,559,721.88	0.46%
IDEXX Laboratories, Inc.	IDXX	45168D104	Medical Equipment and Services	8,313	$4,530,585.00	0.46%
Amgen Inc.	AMGN	031162100	Pharmaceuticals and Biotechnology	12,084	$4,423,348.20	0.45%
BioMarin Pharmaceutical Inc.	BMRN	09061G101	Pharmaceuticals and Biotechnology	76,477	$4,466,256.80	0.45%
Envista Holdings Corporation	NVST	29415F104	Medical Equipment and Services	166,075	$4,389,362.25	0.44%
Johnson & Johnson	JNJ	478160104	Pharmaceuticals and Biotechnology	17,232	$4,405,016.16	0.44%
Merck & Co., Inc.	MRK	58933Y105	Pharmaceuticals and Biotechnology	34,055	$4,340,990.85	0.44%
Revvity, Inc.	RVTY	714046109	Medical Equipment and Services	39,331	$4,347,648.74	0.44%
West Pharmaceutical Services, Inc.	WST	955306105	Medical Equipment and Services	12,190	$4,369,017.90	0.44%
Stryker Corporation	SYK	863667101	Medical Equipment and Services	13,898	$4,297,817.52	0.43%
The Cooper Companies, Inc.	COO	216648501	Medical Equipment and Services	61,023	$4,302,121.50	0.43%
Danaher Corporation	DHR	235851102	Medical Equipment and Services	22,974	$4,115,562.36	0.41%
US Dollar	$USD		Other	2,230,655	$2,230,654.82	0.22%

Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.