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Total Number of Holdings (excluding cash): 49
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
21,111 |
$2,344,798.77 |
7.63% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
14,634 |
$2,258,757.90 |
7.35% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
55,284 |
$2,078,678.40 |
6.77% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
32,525 |
$2,075,745.50 |
6.76% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
14,574 |
$2,004,799.44 |
6.53% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
3,604 |
$1,534,547.16 |
5.00% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
3,863 |
$1,274,751.37 |
4.15% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
14,813 |
$1,226,960.79 |
3.99% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
3,712 |
$1,108,625.92 |
3.61% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
6,715 |
$1,106,229.10 |
3.60% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
13,926 |
$1,073,555.34 |
3.49% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,475 |
$1,069,448.75 |
3.48% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
4,841 |
$1,050,158.13 |
3.42% |
| Moderna, Inc. |
MRNA |
60770K107 |
Biotechnology |
8,079 |
$1,019,892.96 |
3.32% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
98,373 |
$896,178.03 |
2.92% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
6,960 |
$876,264.00 |
2.85% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
9,313 |
$582,807.54 |
1.90% |
| Organon & Co. |
OGN |
68622V106 |
Pharmaceuticals |
29,116 |
$568,926.64 |
1.85% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
2,580 |
$534,885.60 |
1.74% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
2,327 |
$451,717.24 |
1.47% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
1,774 |
$361,097.70 |
1.18% |
| Syneos Health, Inc. |
SYNH |
87166B102 |
Biotechnology |
8,266 |
$343,865.60 |
1.12% |
| IVERIC bio, Inc. |
ISEE |
46583P102 |
Biotechnology |
7,501 |
$283,237.76 |
0.92% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
14,589 |
$279,087.57 |
0.91% |
| Prometheus Biosciences, Inc. |
RXDX |
74349U108 |
Biotechnology |
1,274 |
$253,016.40 |
0.82% |
| Exact Sciences Corporation |
EXAS |
30063P105 |
Biotechnology |
2,501 |
$205,107.01 |
0.67% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
6,331 |
$205,061.09 |
0.67% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
3,410 |
$201,292.30 |
0.66% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
7,534 |
$186,692.52 |
0.61% |
| Vaxcyte, Inc. |
PCVX |
92243G108 |
Biotechnology |
3,804 |
$186,281.88 |
0.61% |
| Prothena Corporation Plc |
PRTA |
G72800108 |
Biotechnology |
2,796 |
$185,766.24 |
0.60% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
4,342 |
$176,893.08 |
0.58% |
| Roivant Sciences Ltd. |
ROIV |
G76279101 |
Biotechnology |
19,268 |
$179,385.08 |
0.58% |
| Vir Biotechnology, Inc. |
VIR |
92764N102 |
Biotechnology |
6,837 |
$178,103.85 |
0.58% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
5,829 |
$170,906.28 |
0.56% |
| Karuna Therapeutics, Inc. |
KRTX |
48576A100 |
Biotechnology |
781 |
$171,952.77 |
0.56% |
| Seagen Inc. |
SGEN |
81181C104 |
Pharmaceuticals |
868 |
$167,949.32 |
0.55% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
1,802 |
$164,378.44 |
0.54% |
| Sarepta Therapeutics, Inc. |
SRPT |
803607100 |
Biotechnology |
1,276 |
$161,822.32 |
0.53% |
| Axsome Therapeutics, Inc. |
AXSM |
05464T104 |
Biotechnology |
2,286 |
$159,562.80 |
0.52% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
814 |
$153,243.64 |
0.50% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
3,569 |
$152,253.54 |
0.50% |
| NovoCure Limited |
NVCR |
G6674U108 |
Biotechnology |
2,026 |
$149,032.56 |
0.49% |
| Catalent, Inc. |
CTLT |
148806102 |
Pharmaceuticals |
3,953 |
$146,735.36 |
0.48% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
4,476 |
$148,603.20 |
0.48% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
1,565 |
$138,479.04 |
0.45% |
| Amicus Therapeutics, Inc. |
FOLD |
03152W109 |
Biotechnology |
11,818 |
$131,297.98 |
0.43% |
| Harmony Biosciences Holdings, Inc. |
HRMY |
413197104 |
Pharmaceuticals |
3,540 |
$125,882.40 |
0.41% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
13,590 |
$113,068.80 |
0.37% |
| US Dollar |
$USD |
|
Other |
102,615 |
$102,615.19 |
0.33% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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