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Total Number of Holdings (excluding cash): 50
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
18,081 |
$2,157,244.11 |
8.24% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
8,584 |
$2,067,542.24 |
7.89% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
32,239 |
$1,932,083.27 |
7.38% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
61,431 |
$1,703,481.63 |
6.50% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
7,230 |
$1,597,034.70 |
6.10% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
72,089 |
$1,162,795.57 |
4.44% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
5,112 |
$1,146,366.00 |
4.38% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
5,646 |
$1,079,515.20 |
4.12% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
1,038 |
$1,053,787.98 |
4.02% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
6,733 |
$1,049,001.40 |
4.00% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,309 |
$1,019,671.73 |
3.89% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
2,643 |
$968,870.94 |
3.70% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
1,946 |
$897,573.04 |
3.43% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,701 |
$809,420.85 |
3.09% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
4,862 |
$625,593.54 |
2.39% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
3,576 |
$594,474.24 |
2.27% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
3,790 |
$441,080.20 |
1.68% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
5,433 |
$385,308.36 |
1.47% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
3,846 |
$380,138.64 |
1.45% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
7,577 |
$325,356.38 |
1.24% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
1,864 |
$309,386.72 |
1.18% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
11,778 |
$302,812.38 |
1.16% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
4,699 |
$289,223.45 |
1.10% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
4,443 |
$267,957.33 |
1.02% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
2,894 |
$230,101.94 |
0.88% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
6,424 |
$224,261.84 |
0.86% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
508 |
$215,356.44 |
0.82% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
14,195 |
$208,666.50 |
0.80% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
2,429 |
$204,886.15 |
0.78% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
702 |
$191,400.30 |
0.73% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,534 |
$165,027.72 |
0.63% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
1,184 |
$162,728.96 |
0.62% |
| BridgeBio Pharma, Inc. |
BBIO |
10806X102 |
Biotechnology |
1,999 |
$146,586.67 |
0.56% |
| NewAmsterdam Pharma Company N.V. |
NAMS |
N62509109 |
Biotechnology |
4,305 |
$147,403.20 |
0.56% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,754 |
$146,441.46 |
0.56% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,400 |
$139,832.00 |
0.53% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
5,172 |
$123,765.96 |
0.47% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
641 |
$119,200.36 |
0.46% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
2,295 |
$117,825.30 |
0.45% |
| Madrigal Pharmaceuticals, Inc. |
MDGL |
558868105 |
Biotechnology |
237 |
$113,997.00 |
0.44% |
| Insmed Incorporated |
INSM |
457669307 |
Biotechnology |
762 |
$113,103.66 |
0.43% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
1,619 |
$106,805.43 |
0.41% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
3,529 |
$101,705.78 |
0.39% |
| Rhythm Pharmaceuticals, Inc. |
RYTM |
76243J105 |
Biotechnology |
1,004 |
$98,863.88 |
0.38% |
| ADMA Biologics, Inc. |
ADMA |
000899104 |
Biotechnology |
5,998 |
$97,647.44 |
0.37% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
3,985 |
$89,542.95 |
0.34% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
5,652 |
$82,519.20 |
0.32% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
230 |
$74,124.40 |
0.28% |
| Tempus AI, Inc. (Class A) |
TEM |
88023B103 |
Biotechnology |
1,365 |
$73,177.65 |
0.28% |
| US Dollar |
$USD |
|
Other |
73,125 |
$73,124.50 |
0.28% |
| Corcept Therapeutics Inc. |
CORT |
218352102 |
Pharmaceuticals |
1,485 |
$60,632.55 |
0.23% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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