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Total Number of Holdings (excluding cash): 50
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
14,477 |
$1,443,646.44 |
7.39% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
6,874 |
$1,388,066.82 |
7.11% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
25,812 |
$1,346,095.80 |
6.89% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
5,788 |
$1,308,551.04 |
6.70% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
49,185 |
$1,280,285.55 |
6.56% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
831 |
$839,567.61 |
4.30% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
4,522 |
$819,838.60 |
4.20% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
4,093 |
$813,811.19 |
4.17% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,048 |
$752,841.28 |
3.86% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
1,557 |
$709,182.36 |
3.63% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
2,116 |
$698,047.24 |
3.58% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,363 |
$666,929.53 |
3.42% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
5,390 |
$653,375.80 |
3.35% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
57,716 |
$630,835.88 |
3.23% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
2,864 |
$486,020.80 |
2.49% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
3,893 |
$461,904.45 |
2.37% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
3,034 |
$391,264.64 |
2.00% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
4,349 |
$335,982.01 |
1.72% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
3,081 |
$315,864.12 |
1.62% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
1,493 |
$275,174.83 |
1.41% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
6,067 |
$269,132.12 |
1.38% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
3,763 |
$231,198.72 |
1.18% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
406 |
$222,536.72 |
1.14% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
9,430 |
$206,517.00 |
1.06% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
3,559 |
$190,050.60 |
0.97% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
1,944 |
$158,785.92 |
0.81% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
5,144 |
$151,850.88 |
0.78% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
948 |
$147,423.48 |
0.76% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
2,317 |
$146,735.61 |
0.75% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
11,366 |
$138,437.88 |
0.71% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
561 |
$131,346.93 |
0.67% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,229 |
$125,382.58 |
0.64% |
| Insmed Incorporated |
INSM |
457669307 |
Biotechnology |
609 |
$124,236.00 |
0.64% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,404 |
$125,868.60 |
0.64% |
| NewAmsterdam Pharma Company N.V. |
NAMS |
N62509109 |
Biotechnology |
3,446 |
$121,505.96 |
0.62% |
| BridgeBio Pharma, Inc. |
BBIO |
10806X102 |
Biotechnology |
1,601 |
$117,897.64 |
0.60% |
| Madrigal Pharmaceuticals, Inc. |
MDGL |
558868105 |
Biotechnology |
190 |
$109,687.00 |
0.56% |
| Corcept Therapeutics Inc. |
CORT |
218352102 |
Pharmaceuticals |
1,189 |
$102,378.85 |
0.52% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
4,140 |
$97,414.20 |
0.50% |
| ADMA Biologics, Inc. |
ADMA |
000899104 |
Biotechnology |
4,802 |
$95,319.70 |
0.49% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
513 |
$94,838.31 |
0.49% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
3,189 |
$87,506.16 |
0.45% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
2,827 |
$86,958.52 |
0.45% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
185 |
$84,752.20 |
0.43% |
| Rhythm Pharmaceuticals, Inc. |
RYTM |
76243J105 |
Biotechnology |
804 |
$84,098.40 |
0.43% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
1,837 |
$83,914.16 |
0.43% |
| Tempus AI, Inc. (Class A) |
TEM |
88023B103 |
Biotechnology |
1,093 |
$83,789.38 |
0.43% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
1,296 |
$78,822.72 |
0.40% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,123 |
$76,903.04 |
0.39% |
| US Dollar |
$USD |
|
Other |
72,032 |
$72,032.48 |
0.37% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
4,525 |
$60,816.00 |
0.31% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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