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Total Number of Holdings (excluding cash): 50
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
15,671 |
$1,705,474.93 |
7.90% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
7,440 |
$1,626,830.40 |
7.54% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
27,941 |
$1,544,019.66 |
7.16% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
53,241 |
$1,365,631.65 |
6.33% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
6,266 |
$1,343,117.10 |
6.22% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
4,430 |
$941,153.50 |
4.36% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
900 |
$934,560.00 |
4.33% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,135 |
$832,000.40 |
3.86% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
4,894 |
$804,671.48 |
3.73% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
62,477 |
$803,454.22 |
3.72% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
2,291 |
$756,969.31 |
3.51% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
1,686 |
$744,132.96 |
3.45% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
5,835 |
$728,849.85 |
3.38% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,475 |
$685,771.75 |
3.18% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
3,100 |
$525,171.00 |
2.43% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
4,214 |
$525,275.10 |
2.43% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
3,284 |
$465,178.60 |
2.16% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
1,616 |
$355,035.20 |
1.65% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
3,334 |
$354,104.14 |
1.64% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
4,709 |
$341,308.32 |
1.58% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
6,567 |
$288,685.32 |
1.34% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
440 |
$268,796.00 |
1.25% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
4,073 |
$260,020.32 |
1.21% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
10,208 |
$250,402.24 |
1.16% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
3,851 |
$210,226.09 |
0.97% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
2,508 |
$178,594.68 |
0.83% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
5,568 |
$176,115.84 |
0.82% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
608 |
$173,304.32 |
0.80% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
12,303 |
$164,983.23 |
0.76% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
2,105 |
$160,674.65 |
0.74% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,330 |
$149,146.20 |
0.69% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
1,026 |
$135,832.14 |
0.63% |
| BridgeBio Pharma, Inc. |
BBIO |
10806X102 |
Biotechnology |
1,733 |
$132,158.58 |
0.61% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,520 |
$124,624.80 |
0.58% |
| NewAmsterdam Pharma Company N.V. |
NAMS |
N62509109 |
Biotechnology |
3,731 |
$118,086.15 |
0.55% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,214 |
$110,534.70 |
0.51% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
555 |
$107,098.35 |
0.50% |
| Insmed Incorporated |
INSM |
457669307 |
Biotechnology |
660 |
$106,537.20 |
0.49% |
| Madrigal Pharmaceuticals, Inc. |
MDGL |
558868105 |
Biotechnology |
205 |
$102,844.40 |
0.48% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
4,482 |
$101,741.40 |
0.47% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
1,989 |
$99,450.00 |
0.46% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
3,059 |
$93,513.63 |
0.43% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
3,453 |
$89,743.47 |
0.42% |
| ADMA Biologics, Inc. |
ADMA |
000899104 |
Biotechnology |
5,198 |
$89,977.38 |
0.42% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
1,403 |
$91,363.36 |
0.42% |
| Rhythm Pharmaceuticals, Inc. |
RYTM |
76243J105 |
Biotechnology |
870 |
$88,418.10 |
0.41% |
| Tempus AI, Inc. (Class A) |
TEM |
88023B103 |
Biotechnology |
1,183 |
$83,200.39 |
0.39% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
4,898 |
$73,616.94 |
0.34% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
200 |
$71,854.00 |
0.33% |
| US Dollar |
$USD |
|
Other |
48,094 |
$48,094.49 |
0.22% |
| Corcept Therapeutics Inc. |
CORT |
218352102 |
Pharmaceuticals |
1,287 |
$44,697.51 |
0.21% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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