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Total Number of Holdings (excluding cash): 50
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
20,535 |
$2,379,390.45 |
8.24% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
9,751 |
$2,321,810.61 |
8.04% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
36,614 |
$2,186,221.94 |
7.57% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
69,767 |
$1,915,104.15 |
6.63% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
8,210 |
$1,804,229.60 |
6.25% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
5,805 |
$1,255,969.80 |
4.35% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
6,413 |
$1,188,264.77 |
4.12% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,487 |
$1,128,707.35 |
3.91% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
81,869 |
$1,129,792.20 |
3.91% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
7,631 |
$1,101,916.40 |
3.82% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
1,179 |
$1,096,882.65 |
3.80% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
3,002 |
$1,084,112.26 |
3.76% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,934 |
$1,044,398.68 |
3.62% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
2,206 |
$1,020,252.94 |
3.53% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
4,052 |
$734,911.24 |
2.55% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
5,510 |
$670,456.80 |
2.32% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
4,296 |
$519,128.64 |
1.80% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
6,157 |
$415,289.65 |
1.44% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
4,358 |
$410,610.76 |
1.42% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
8,587 |
$359,194.21 |
1.24% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
13,348 |
$336,102.64 |
1.16% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
2,112 |
$324,635.52 |
1.12% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
5,325 |
$306,560.25 |
1.06% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
5,035 |
$282,211.75 |
0.98% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
576 |
$262,166.40 |
0.91% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
3,280 |
$213,626.40 |
0.74% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
796 |
$204,038.68 |
0.71% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
7,280 |
$201,292.00 |
0.70% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
16,087 |
$199,961.41 |
0.69% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
2,753 |
$199,124.49 |
0.69% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,988 |
$193,293.24 |
0.67% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
1,342 |
$175,412.82 |
0.61% |
| BridgeBio Pharma, Inc. |
BBIO |
10806X102 |
Biotechnology |
2,265 |
$160,679.10 |
0.56% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,738 |
$154,247.50 |
0.53% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
727 |
$153,389.73 |
0.53% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,586 |
$153,128.30 |
0.53% |
| NewAmsterdam Pharma Company N.V. |
NAMS |
N62509109 |
Biotechnology |
4,879 |
$149,297.40 |
0.52% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
5,862 |
$136,760.46 |
0.47% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
2,601 |
$132,182.82 |
0.46% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
3,999 |
$126,008.49 |
0.44% |
| Insmed Incorporated |
INSM |
457669307 |
Biotechnology |
864 |
$124,355.52 |
0.43% |
| Madrigal Pharmaceuticals, Inc. |
MDGL |
558868105 |
Biotechnology |
269 |
$119,215.42 |
0.41% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
1,835 |
$114,320.50 |
0.40% |
| ADMA Biologics, Inc. |
ADMA |
000899104 |
Biotechnology |
6,798 |
$109,787.70 |
0.38% |
| Rhythm Pharmaceuticals, Inc. |
RYTM |
76243J105 |
Biotechnology |
1,138 |
$99,779.84 |
0.35% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
4,517 |
$94,405.30 |
0.33% |
| US Dollar |
$USD |
|
Other |
86,848 |
$86,848.04 |
0.30% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
260 |
$83,309.20 |
0.29% |
| Tempus AI, Inc. (Class A) |
TEM |
88023B103 |
Biotechnology |
1,547 |
$78,649.48 |
0.27% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
6,406 |
$65,981.80 |
0.23% |
| Corcept Therapeutics Inc. |
CORT |
218352102 |
Pharmaceuticals |
1,683 |
$56,397.33 |
0.20% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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