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Total Number of Holdings (excluding cash): 50
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
19,286 |
$2,341,513.26 |
8.31% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
9,156 |
$2,229,028.20 |
7.91% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
34,388 |
$2,088,727.12 |
7.41% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
65,526 |
$1,807,207.08 |
6.42% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
7,712 |
$1,785,328.00 |
6.34% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
76,895 |
$1,212,634.15 |
4.30% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
5,453 |
$1,203,967.87 |
4.27% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
6,022 |
$1,183,443.44 |
4.20% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
1,107 |
$1,151,280.00 |
4.09% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,396 |
$1,121,225.32 |
3.98% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
7,182 |
$1,113,066.36 |
3.95% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
2,819 |
$1,040,746.61 |
3.69% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
2,076 |
$1,020,291.72 |
3.62% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,814 |
$859,219.24 |
3.05% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
5,186 |
$656,806.90 |
2.33% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
3,814 |
$634,306.34 |
2.25% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
4,043 |
$472,262.83 |
1.68% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
4,102 |
$414,712.20 |
1.47% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
5,795 |
$402,462.75 |
1.43% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
8,082 |
$354,961.44 |
1.26% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
5,012 |
$319,865.84 |
1.14% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
1,988 |
$320,763.80 |
1.14% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
12,563 |
$315,708.19 |
1.12% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
4,739 |
$283,723.93 |
1.01% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
3,087 |
$245,231.28 |
0.87% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
542 |
$231,992.26 |
0.82% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
6,852 |
$227,212.32 |
0.81% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
15,141 |
$224,389.62 |
0.80% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
2,591 |
$208,834.60 |
0.74% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
749 |
$207,061.05 |
0.74% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,636 |
$171,534.60 |
0.61% |
| BridgeBio Pharma, Inc. |
BBIO |
10806X102 |
Biotechnology |
2,132 |
$160,433.00 |
0.57% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
1,263 |
$156,763.56 |
0.56% |
| NewAmsterdam Pharma Company N.V. |
NAMS |
N62509109 |
Biotechnology |
4,592 |
$159,020.96 |
0.56% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,493 |
$153,928.30 |
0.55% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,871 |
$152,467.79 |
0.54% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
5,517 |
$134,228.61 |
0.48% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
684 |
$125,739.72 |
0.45% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
2,448 |
$124,456.32 |
0.44% |
| Insmed Incorporated |
INSM |
457669307 |
Biotechnology |
813 |
$120,933.75 |
0.43% |
| Madrigal Pharmaceuticals, Inc. |
MDGL |
558868105 |
Biotechnology |
253 |
$117,571.63 |
0.42% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
1,727 |
$115,346.33 |
0.41% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
3,764 |
$107,274.00 |
0.38% |
| ADMA Biologics, Inc. |
ADMA |
000899104 |
Biotechnology |
6,398 |
$102,943.82 |
0.37% |
| Rhythm Pharmaceuticals, Inc. |
RYTM |
76243J105 |
Biotechnology |
1,071 |
$105,032.97 |
0.37% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
4,251 |
$93,649.53 |
0.33% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
6,029 |
$87,661.66 |
0.31% |
| US Dollar |
$USD |
|
Other |
87,459 |
$87,459.19 |
0.31% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
245 |
$77,028.00 |
0.27% |
| Tempus AI, Inc. (Class A) |
TEM |
88023B103 |
Biotechnology |
1,456 |
$75,639.20 |
0.27% |
| Corcept Therapeutics Inc. |
CORT |
218352102 |
Pharmaceuticals |
1,584 |
$63,312.48 |
0.22% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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