First Trust Nasdaq Pharmaceuticals ETF (FTXH)

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Holdings

Holdings of the Fund as of 12/8/2025
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Total Number of Holdings (excluding cash): 50

Security Name	Identifier	CUSIP	Classification	Shares / Quantity	Market Value	Weighting
Merck & Co., Inc.	MRK	58933Y105	Pharmaceuticals	14,477	$1,432,209.61	7.40%
Johnson & Johnson	JNJ	478160104	Pharmaceuticals	6,874	$1,385,935.88	7.16%
Bristol-Myers Squibb Company	BMY	110122108	Pharmaceuticals	25,812	$1,333,706.04	6.89%
AbbVie Inc.	ABBV	00287Y109	Pharmaceuticals	5,788	$1,291,418.56	6.67%
Pfizer Inc.	PFE	717081103	Pharmaceuticals	49,185	$1,267,497.45	6.55%
Eli Lilly and Company	LLY	532457108	Pharmaceuticals	831	$828,997.29	4.28%
Biogen Inc.	BIIB	09062X103	Biotechnology	4,522	$815,949.68	4.21%
Cardinal Health, Inc.	CAH	14149Y108	Pharmaceuticals	4,093	$814,015.84	4.20%
Regeneron Pharmaceuticals, Inc.	REGN	75886F107	Biotechnology	1,048	$737,016.48	3.81%
Vertex Pharmaceuticals Incorporated	VRTX	92532F100	Pharmaceuticals	1,557	$688,256.28	3.55%
Amgen Inc.	AMGN	031162100	Pharmaceuticals	2,116	$679,722.68	3.51%
United Therapeutics Corporation	UTHR	91307C102	Pharmaceuticals	1,363	$653,572.13	3.38%
Gilead Sciences, Inc.	GILD	375558103	Pharmaceuticals	5,390	$653,214.10	3.37%
Viatris Inc.	VTRS	92556V106	Pharmaceuticals	57,716	$640,070.44	3.31%
Jazz Pharmaceuticals Plc	JAZZ	G50871105	Pharmaceuticals	2,864	$483,844.16	2.50%
Zoetis Inc.	ZTS	98978V103	Pharmaceuticals	3,893	$459,996.88	2.38%
Illumina, Inc.	ILMN	452327109	Biotechnology	3,034	$386,076.50	1.99%
PTC Therapeutics, Inc.	PTCT	69366J200	Biotechnology	4,349	$334,481.59	1.73%
Incyte Corporation	INCY	45337C102	Biotechnology	3,081	$297,932.70	1.54%
Charles River Laboratories International, Inc.	CRL	159864107	Biotechnology	1,493	$279,370.16	1.44%
Arrowhead Pharmaceuticals, Inc.	ARWR	04280A100	Biotechnology	3,763	$258,141.80	1.33%
Exelixis, Inc.	EXEL	30161Q104	Biotechnology	6,067	$255,845.39	1.32%
Medpace Holdings, Inc.	MEDP	58506Q109	Biotechnology	406	$222,963.02	1.15%
Elanco Animal Health Incorporated	ELAN	28414H103	Pharmaceuticals	9,430	$204,536.70	1.06%
BioMarin Pharmaceutical Inc.	BMRN	09061G101	Pharmaceuticals	3,559	$189,694.70	0.98%
Ionis Pharmaceuticals, Inc.	IONS	462222100	Pharmaceuticals	1,944	$158,455.44	0.82%
Alkermes Plc	ALKS	G01767105	Pharmaceuticals	5,144	$151,285.04	0.78%
Neurocrine Biosciences, Inc.	NBIX	64125C109	Biotechnology	948	$146,930.52	0.76%
Halozyme Therapeutics, Inc.	HALO	40637H109	Biotechnology	2,317	$145,692.96	0.75%
Amneal Pharmaceuticals, Inc.	AMRX	03168L105	Pharmaceuticals	11,366	$134,914.42	0.70%
Krystal Biotech, Inc.	KRYS	501147102	Biotechnology	561	$131,302.05	0.68%
Guardant Health, Inc.	GH	40131M109	Biotechnology	1,229	$128,024.93	0.66%
Protagonist Therapeutics, Inc.	PTGX	74366E102	Biotechnology	1,404	$126,711.00	0.65%
NewAmsterdam Pharma Company N.V.	NAMS	N62509109	Biotechnology	3,446	$123,194.50	0.64%
Insmed Incorporated	INSM	457669307	Biotechnology	609	$119,698.95	0.62%
BridgeBio Pharma, Inc.	BBIO	10806X102	Biotechnology	1,601	$118,858.24	0.61%
Madrigal Pharmaceuticals, Inc.	MDGL	558868105	Biotechnology	190	$108,028.30	0.56%
Corcept Therapeutics Inc.	CORT	218352102	Pharmaceuticals	1,189	$98,663.22	0.51%
Catalyst Pharmaceuticals, Inc.	CPRX	14888U101	Biotechnology	4,140	$95,882.40	0.50%
Ligand Pharmaceuticals Inc. (Class B)	LGND	53220K504	Biotechnology	513	$94,735.71	0.49%
ADMA Biologics, Inc.	ADMA	000899104	Biotechnology	4,802	$93,110.78	0.48%
Supernus Pharmaceuticals, Inc.	SUPN	868459108	Pharmaceuticals	1,837	$86,632.92	0.45%
TG Therapeutics, Inc.	TGTX	88322Q108	Biotechnology	2,827	$87,156.41	0.45%
ACADIA Pharmaceuticals Inc.	ACAD	004225108	Biotechnology	3,189	$85,337.64	0.44%
Rhythm Pharmaceuticals, Inc.	RYTM	76243J105	Biotechnology	804	$84,564.72	0.44%
Tempus AI, Inc. (Class A)	TEM	88023B103	Biotechnology	1,093	$84,204.72	0.43%
Alnylam Pharmaceuticals, Inc.	ALNY	02043Q107	Biotechnology	185	$79,553.70	0.41%
Prestige Consumer Healthcare Inc.	PBH	74112D101	Pharmaceuticals	1,296	$78,161.76	0.40%
Mirum Pharmaceuticals, Inc.	MIRM	604749101	Biotechnology	1,123	$76,251.70	0.39%
US Dollar	$USD		Other	72,032	$72,032.48	0.37%
Perrigo Company Plc	PRGO	G97822103	Pharmaceuticals	4,525	$59,187.00	0.31%

Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.