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Total Number of Holdings (excluding cash): 50
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
14,477 |
$1,480,562.79 |
7.53% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
6,874 |
$1,411,438.42 |
7.18% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
5,788 |
$1,332,629.12 |
6.78% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
25,812 |
$1,315,379.52 |
6.69% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
49,185 |
$1,257,660.45 |
6.40% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
831 |
$858,888.36 |
4.37% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
4,522 |
$817,351.50 |
4.16% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
4,093 |
$817,413.03 |
4.16% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,048 |
$758,406.16 |
3.86% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
2,116 |
$730,908.72 |
3.72% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
1,557 |
$721,093.41 |
3.67% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
5,390 |
$673,750.00 |
3.43% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,363 |
$655,548.48 |
3.33% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
57,716 |
$625,641.44 |
3.18% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
2,864 |
$478,574.40 |
2.43% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
3,893 |
$477,165.01 |
2.43% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
3,034 |
$388,200.30 |
1.97% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
4,349 |
$329,480.24 |
1.68% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
3,081 |
$312,721.50 |
1.59% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
1,493 |
$275,712.31 |
1.40% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
6,067 |
$267,008.67 |
1.36% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
3,763 |
$244,877.23 |
1.25% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
406 |
$234,054.94 |
1.19% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
9,430 |
$209,157.40 |
1.06% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
3,559 |
$193,289.29 |
0.98% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
1,944 |
$159,096.96 |
0.81% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
5,144 |
$151,902.32 |
0.77% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
2,317 |
$149,817.22 |
0.76% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
948 |
$144,058.08 |
0.73% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
11,366 |
$138,437.88 |
0.70% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,229 |
$130,224.84 |
0.66% |
| Insmed Incorporated |
INSM |
457669307 |
Biotechnology |
609 |
$125,929.02 |
0.64% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
561 |
$121,995.06 |
0.62% |
| NewAmsterdam Pharma Company N.V. |
NAMS |
N62509109 |
Biotechnology |
3,446 |
$122,401.92 |
0.62% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,404 |
$120,842.28 |
0.61% |
| BridgeBio Pharma, Inc. |
BBIO |
10806X102 |
Biotechnology |
1,601 |
$118,714.15 |
0.60% |
| Madrigal Pharmaceuticals, Inc. |
MDGL |
558868105 |
Biotechnology |
190 |
$110,179.10 |
0.56% |
| Corcept Therapeutics Inc. |
CORT |
218352102 |
Pharmaceuticals |
1,189 |
$99,483.63 |
0.51% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
513 |
$99,024.39 |
0.50% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
4,140 |
$95,634.00 |
0.49% |
| ADMA Biologics, Inc. |
ADMA |
000899104 |
Biotechnology |
4,802 |
$94,695.44 |
0.48% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
185 |
$87,558.65 |
0.45% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
2,827 |
$89,361.47 |
0.45% |
| Rhythm Pharmaceuticals, Inc. |
RYTM |
76243J105 |
Biotechnology |
804 |
$84,122.52 |
0.43% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
3,189 |
$82,531.32 |
0.42% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
1,837 |
$82,224.12 |
0.42% |
| Tempus AI, Inc. (Class A) |
TEM |
88023B103 |
Biotechnology |
1,093 |
$81,876.63 |
0.42% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,123 |
$79,721.77 |
0.41% |
| US Dollar |
$USD |
|
Other |
81,303 |
$81,302.63 |
0.41% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
1,296 |
$78,122.88 |
0.40% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
4,525 |
$63,169.00 |
0.32% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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