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Total Number of Holdings (excluding cash): 50
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
15,671 |
$1,711,116.49 |
7.87% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
7,440 |
$1,560,316.80 |
7.18% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
27,941 |
$1,558,269.57 |
7.17% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
6,266 |
$1,378,770.64 |
6.34% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
53,241 |
$1,345,400.07 |
6.19% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
900 |
$972,900.00 |
4.48% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
4,894 |
$908,473.22 |
4.18% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
4,430 |
$897,163.60 |
4.13% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,135 |
$871,680.00 |
4.01% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
62,477 |
$792,208.36 |
3.65% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
1,686 |
$776,554.74 |
3.57% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
2,291 |
$745,812.14 |
3.43% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
5,835 |
$715,371.00 |
3.29% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,475 |
$711,525.25 |
3.27% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
4,214 |
$528,098.48 |
2.43% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
3,100 |
$507,408.00 |
2.33% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
3,284 |
$477,986.20 |
2.20% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
4,709 |
$365,371.31 |
1.68% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
1,616 |
$353,613.12 |
1.63% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
3,334 |
$354,504.22 |
1.63% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
6,567 |
$289,342.02 |
1.33% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
4,073 |
$268,532.89 |
1.24% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
440 |
$263,652.40 |
1.21% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
10,208 |
$243,664.96 |
1.12% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
3,851 |
$222,241.21 |
1.02% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
2,508 |
$181,629.36 |
0.84% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
2,105 |
$171,894.30 |
0.79% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
5,568 |
$164,924.16 |
0.76% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
608 |
$165,455.04 |
0.76% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
12,303 |
$159,692.94 |
0.73% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,330 |
$143,068.10 |
0.66% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
1,026 |
$136,109.16 |
0.63% |
| BridgeBio Pharma, Inc. |
BBIO |
10806X102 |
Biotechnology |
1,733 |
$133,163.72 |
0.61% |
| NewAmsterdam Pharma Company N.V. |
NAMS |
N62509109 |
Biotechnology |
3,731 |
$121,966.39 |
0.56% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,520 |
$121,980.00 |
0.56% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
555 |
$114,779.55 |
0.53% |
| Insmed Incorporated |
INSM |
457669307 |
Biotechnology |
660 |
$110,695.20 |
0.51% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,214 |
$108,653.00 |
0.50% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
4,482 |
$104,072.04 |
0.48% |
| Madrigal Pharmaceuticals, Inc. |
MDGL |
558868105 |
Biotechnology |
205 |
$104,658.65 |
0.48% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
1,989 |
$102,155.04 |
0.47% |
| ADMA Biologics, Inc. |
ADMA |
000899104 |
Biotechnology |
5,198 |
$93,200.14 |
0.43% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
3,453 |
$91,815.27 |
0.42% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
1,403 |
$91,615.90 |
0.42% |
| Rhythm Pharmaceuticals, Inc. |
RYTM |
76243J105 |
Biotechnology |
870 |
$91,254.30 |
0.42% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
3,059 |
$84,795.48 |
0.39% |
| Tempus AI, Inc. (Class A) |
TEM |
88023B103 |
Biotechnology |
1,183 |
$81,934.58 |
0.38% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
200 |
$74,182.00 |
0.34% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
4,898 |
$73,176.12 |
0.34% |
| Corcept Therapeutics Inc. |
CORT |
218352102 |
Pharmaceuticals |
1,287 |
$48,082.32 |
0.22% |
| US Dollar |
$USD |
|
Other |
37,254 |
$37,254.31 |
0.17% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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