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Total Number of Holdings (excluding cash): 50
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
37,506 |
$2,185,099.56 |
7.25% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
9,416 |
$2,144,870.64 |
7.12% |
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
18,893 |
$2,078,796.79 |
6.90% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
10,080 |
$1,992,715.20 |
6.61% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
2,224 |
$1,943,776.00 |
6.45% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
78,341 |
$1,161,013.62 |
3.85% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
42,301 |
$1,120,130.48 |
3.72% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
6,098 |
$1,118,251.24 |
3.71% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,496 |
$1,094,727.92 |
3.63% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
5,102 |
$1,049,022.22 |
3.48% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
8,922 |
$1,040,751.30 |
3.45% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
3,013 |
$1,023,124.41 |
3.40% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
7,852 |
$1,014,949.52 |
3.37% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
2,354 |
$1,012,549.56 |
3.36% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,726 |
$982,283.86 |
3.26% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
3,544 |
$722,905.12 |
2.40% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
7,246 |
$708,224.04 |
2.35% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
3,872 |
$491,434.24 |
1.63% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
10,884 |
$489,018.12 |
1.62% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
5,770 |
$405,400.20 |
1.35% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
2,252 |
$375,611.08 |
1.25% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
916 |
$375,239.40 |
1.25% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
6,690 |
$356,577.00 |
1.18% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
2,785 |
$356,814.20 |
1.18% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
5,299 |
$338,394.14 |
1.12% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
8,873 |
$302,924.22 |
1.01% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
11,568 |
$256,231.20 |
0.85% |
| Spyre Therapeutics, Inc. |
SYRE |
00773J202 |
Biotechnology |
3,741 |
$256,744.83 |
0.85% |
| Travere Therapeutics, Inc. |
TVTX |
89422G107 |
Pharmaceuticals |
5,400 |
$220,806.00 |
0.73% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
6,970 |
$205,196.80 |
0.68% |
| Twist Bioscience Corporation |
TWST |
90184D100 |
Biotechnology |
3,428 |
$202,766.20 |
0.67% |
| Arcus Biosciences, Inc. |
RCUS |
03969F109 |
Biotechnology |
7,898 |
$195,870.40 |
0.65% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
2,765 |
$193,909.45 |
0.64% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
811 |
$188,411.52 |
0.63% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
5,346 |
$184,864.68 |
0.61% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,747 |
$176,813.87 |
0.59% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
13,748 |
$175,080.79 |
0.58% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,743 |
$163,842.00 |
0.54% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
583 |
$156,984.41 |
0.52% |
| Roivant Sciences Ltd. |
ROIV |
G76279101 |
Biotechnology |
5,559 |
$154,373.43 |
0.51% |
| 10X Genomics, Inc. (Class A) |
TXG |
88025U109 |
Biotechnology |
6,979 |
$149,141.23 |
0.49% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
6,550 |
$148,488.50 |
0.49% |
| Kymera Therapeutics, Inc. |
KYMR |
501575104 |
Biotechnology |
1,761 |
$147,659.85 |
0.49% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
483 |
$145,919.13 |
0.48% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,713 |
$142,333.17 |
0.47% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
1,982 |
$142,267.96 |
0.47% |
| Moderna, Inc. |
MRNA |
60770K107 |
Biotechnology |
3,003 |
$141,561.42 |
0.47% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
2,939 |
$143,099.91 |
0.47% |
| Arcutis Biotherapeutics, Inc. |
ARQT |
03969K108 |
Biotechnology |
5,964 |
$138,901.56 |
0.46% |
| Tarsus Pharmaceuticals, Inc. |
TARS |
87650L103 |
Biotechnology |
2,130 |
$132,251.70 |
0.44% |
| US Dollar |
$USD |
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Other |
84,546 |
$84,545.70 |
0.28% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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