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Total Number of Holdings (excluding cash): 50
| Merck & Co., Inc. |
MRK |
58933Y105 |
Pharmaceuticals |
16,876 |
$1,825,645.68 |
7.73% |
| Johnson & Johnson |
JNJ |
478160104 |
Pharmaceuticals |
8,012 |
$1,763,761.68 |
7.47% |
| Bristol-Myers Squibb Company |
BMY |
110122108 |
Pharmaceuticals |
30,090 |
$1,644,418.50 |
6.97% |
| AbbVie Inc. |
ABBV |
00287Y109 |
Pharmaceuticals |
6,748 |
$1,479,566.48 |
6.27% |
| Pfizer Inc. |
PFE |
717081103 |
Pharmaceuticals |
57,336 |
$1,470,668.40 |
6.23% |
| Eli Lilly and Company |
LLY |
532457108 |
Pharmaceuticals |
969 |
$1,031,297.01 |
4.37% |
| Cardinal Health, Inc. |
CAH |
14149Y108 |
Pharmaceuticals |
4,771 |
$993,942.43 |
4.21% |
| Regeneron Pharmaceuticals, Inc. |
REGN |
75886F107 |
Biotechnology |
1,222 |
$920,838.10 |
3.90% |
| Biogen Inc. |
BIIB |
09062X103 |
Biotechnology |
5,270 |
$904,279.30 |
3.83% |
| Viatris Inc. |
VTRS |
92556V106 |
Pharmaceuticals |
67,283 |
$888,808.43 |
3.76% |
| Gilead Sciences, Inc. |
GILD |
375558103 |
Pharmaceuticals |
6,284 |
$854,184.12 |
3.62% |
| Amgen Inc. |
AMGN |
031162100 |
Pharmaceuticals |
2,467 |
$850,498.25 |
3.60% |
| Vertex Pharmaceuticals Incorporated |
VRTX |
92532F100 |
Pharmaceuticals |
1,816 |
$850,632.56 |
3.60% |
| United Therapeutics Corporation |
UTHR |
91307C102 |
Pharmaceuticals |
1,588 |
$744,676.72 |
3.15% |
| Jazz Pharmaceuticals Plc |
JAZZ |
G50871105 |
Pharmaceuticals |
3,338 |
$563,153.98 |
2.39% |
| Zoetis Inc. |
ZTS |
98978V103 |
Pharmaceuticals |
4,538 |
$562,938.90 |
2.38% |
| Illumina, Inc. |
ILMN |
452327109 |
Biotechnology |
3,537 |
$531,540.36 |
2.25% |
| Charles River Laboratories International, Inc. |
CRL |
159864107 |
Biotechnology |
1,740 |
$382,121.40 |
1.62% |
| PTC Therapeutics, Inc. |
PTCT |
69366J200 |
Biotechnology |
5,071 |
$381,592.75 |
1.62% |
| Incyte Corporation |
INCY |
45337C102 |
Biotechnology |
3,590 |
$366,144.10 |
1.55% |
| Exelixis, Inc. |
EXEL |
30161Q104 |
Biotechnology |
7,072 |
$313,077.44 |
1.33% |
| Arrowhead Pharmaceuticals, Inc. |
ARWR |
04280A100 |
Biotechnology |
4,386 |
$294,081.30 |
1.25% |
| Medpace Holdings, Inc. |
MEDP |
58506Q109 |
Biotechnology |
474 |
$278,735.70 |
1.18% |
| Elanco Animal Health Incorporated |
ELAN |
28414H103 |
Pharmaceuticals |
10,993 |
$268,229.20 |
1.14% |
| BioMarin Pharmaceutical Inc. |
BMRN |
09061G101 |
Pharmaceuticals |
4,147 |
$233,102.87 |
0.99% |
| Alkermes Plc |
ALKS |
G01767105 |
Pharmaceuticals |
5,996 |
$201,525.56 |
0.85% |
| Halozyme Therapeutics, Inc. |
HALO |
40637H109 |
Biotechnology |
2,701 |
$186,963.22 |
0.79% |
| Krystal Biotech, Inc. |
KRYS |
501147102 |
Biotechnology |
655 |
$184,402.15 |
0.78% |
| Ionis Pharmaceuticals, Inc. |
IONS |
462222100 |
Pharmaceuticals |
2,267 |
$182,006.10 |
0.77% |
| Amneal Pharmaceuticals, Inc. |
AMRX |
03168L105 |
Pharmaceuticals |
13,249 |
$177,404.11 |
0.75% |
| Guardant Health, Inc. |
GH |
40131M109 |
Biotechnology |
1,432 |
$164,322.00 |
0.70% |
| Neurocrine Biosciences, Inc. |
NBIX |
64125C109 |
Biotechnology |
1,105 |
$150,478.90 |
0.64% |
| BridgeBio Pharma, Inc. |
BBIO |
10806X102 |
Biotechnology |
1,866 |
$145,305.42 |
0.62% |
| Protagonist Therapeutics, Inc. |
PTGX |
74366E102 |
Biotechnology |
1,637 |
$136,034.70 |
0.58% |
| NewAmsterdam Pharma Company N.V. |
NAMS |
N62509109 |
Biotechnology |
4,018 |
$133,879.76 |
0.57% |
| Mirum Pharmaceuticals, Inc. |
MIRM |
604749101 |
Biotechnology |
1,307 |
$123,237.03 |
0.52% |
| Ligand Pharmaceuticals Inc. (Class B) |
LGND |
53220K504 |
Biotechnology |
598 |
$120,287.70 |
0.51% |
| Catalyst Pharmaceuticals, Inc. |
CPRX |
14888U101 |
Biotechnology |
4,827 |
$113,820.66 |
0.48% |
| Insmed Incorporated |
INSM |
457669307 |
Biotechnology |
711 |
$111,065.31 |
0.47% |
| Madrigal Pharmaceuticals, Inc. |
MDGL |
558868105 |
Biotechnology |
221 |
$106,179.45 |
0.45% |
| Supernus Pharmaceuticals, Inc. |
SUPN |
868459108 |
Pharmaceuticals |
2,142 |
$103,351.50 |
0.44% |
| TG Therapeutics, Inc. |
TGTX |
88322Q108 |
Biotechnology |
3,294 |
$102,772.80 |
0.44% |
| ACADIA Pharmaceuticals Inc. |
ACAD |
004225108 |
Biotechnology |
3,719 |
$99,817.96 |
0.42% |
| Prestige Consumer Healthcare Inc. |
PBH |
74112D101 |
Pharmaceuticals |
1,511 |
$99,423.80 |
0.42% |
| Rhythm Pharmaceuticals, Inc. |
RYTM |
76243J105 |
Biotechnology |
937 |
$96,389.19 |
0.41% |
| ADMA Biologics, Inc. |
ADMA |
000899104 |
Biotechnology |
5,598 |
$93,654.54 |
0.40% |
| Tempus AI, Inc. (Class A) |
TEM |
88023B103 |
Biotechnology |
1,274 |
$83,217.68 |
0.35% |
| US Dollar |
$USD |
|
Other |
79,112 |
$79,111.87 |
0.34% |
| Alnylam Pharmaceuticals, Inc. |
ALNY |
02043Q107 |
Biotechnology |
215 |
$76,965.70 |
0.33% |
| Perrigo Company Plc |
PRGO |
G97822103 |
Pharmaceuticals |
5,275 |
$77,648.00 |
0.33% |
| Corcept Therapeutics Inc. |
CORT |
218352102 |
Pharmaceuticals |
1,386 |
$60,956.28 |
0.26% |
Holdings are subject to change.
The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.
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The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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