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First Trust NYSE® Arca® Biotechnology Index Fund (FBT)
Holdings of the Fund as of 7/3/2025
View Index Holdings

Total Number of Holdings (excluding cash): 30

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
ACADIA Pharmaceuticals Inc. ACAD 004225108 Health Care 2,150,044 $45,043,421.80 4.41%
Neurocrine Biosciences, Inc. NBIX 64125C109 Health Care 344,973 $44,539,464.03 4.36%
Alnylam Pharmaceuticals, Inc. ALNY 02043Q107 Health Care 131,841 $43,759,346.31 4.29%
Illumina, Inc. ILMN 452327109 Health Care 419,197 $42,255,057.60 4.14%
Exelixis, Inc. EXEL 30161Q104 Health Care 887,782 $40,971,139.30 4.01%
Incyte Corporation INCY 45337C102 Health Care 551,217 $37,730,803.65 3.70%
Exact Sciences Corporation EXAS 30063P105 Health Care 705,235 $37,631,339.60 3.69%
Moderna, Inc. MRNA 60770K107 Health Care 1,196,475 $36,480,522.75 3.57%
Mettler-Toledo International Inc. MTD 592688105 Health Care 30,086 $36,376,380.88 3.56%
Biogen Inc. BIIB 09062X103 Health Care 272,186 $36,165,353.82 3.54%
BioNTech SE (ADR) BNTX 09075V102 Health Care 324,779 $35,725,690.00 3.50%
Bruker Corporation BRKR 116794108 Health Care 808,764 $34,332,031.80 3.36%
Natera, Inc. NTRA 632307104 Health Care 211,750 $34,252,680.00 3.36%
Genmab A/S (ADR) GMAB 372303206 Health Care 1,666,541 $33,830,782.30 3.31%
Gilead Sciences, Inc. GILD 375558103 Health Care 302,497 $33,804,039.75 3.31%
Waters Corporation WAT 941848103 Health Care 96,390 $33,757,705.80 3.31%
Alkermes Plc ALKS G01767105 Health Care 1,161,024 $33,495,542.40 3.28%
BeOne Medicines Ltd. (ADR) ONC 07725L102 Health Care 136,082 $33,406,770.18 3.27%
Corcept Therapeutics Inc. CORT 218352102 Health Care 456,830 $33,015,104.10 3.24%
United Therapeutics Corporation UTHR 91307C102 Health Care 111,494 $32,833,868.06 3.22%
Amgen Inc. AMGN 031162100 Health Care 109,615 $32,691,577.60 3.20%
Repligen Corporation RGEN 759916109 Health Care 255,148 $32,523,715.56 3.19%
BioMarin Pharmaceutical Inc. BMRN 09061G101 Health Care 551,701 $31,722,807.50 3.11%
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Health Care 56,566 $30,961,965.76 3.03%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Health Care 64,739 $29,755,339.18 2.92%
argenx SE (ADR) ARGX 04016X101 Health Care 53,961 $29,326,724.28 2.87%
Halozyme Therapeutics, Inc. HALO 40637H109 Health Care 520,620 $28,113,480.00 2.75%
Krystal Biotech, Inc. KRYS 501147102 Health Care 189,986 $27,183,196.88 2.66%
Veracyte, Inc. VCYT 92337F107 Health Care 985,774 $27,118,642.74 2.66%
Sarepta Therapeutics, Inc. SRPT 803607100 Health Care 614,298 $11,204,795.52 1.10%
US Dollar $USD Other 539,704 $539,703.53 0.05%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.


 
The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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