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First Trust NYSE® Arca® Biotechnology Index Fund (FBT)
Holdings of the Fund as of 3/20/2023
View Index Holdings

Total Number of Holdings (excluding cash): 30

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
Seagen Inc. SGEN 81181C104 Health Care 391,318 $78,424,040.38 5.43%
Exelixis, Inc. EXEL 30161Q104 Health Care 3,075,574 $56,375,271.42 3.91%
Illumina, Inc. ILMN 452327109 Health Care 251,746 $55,326,218.42 3.83%
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Health Care 71,266 $54,108,710.50 3.75%
ACADIA Pharmaceuticals Inc. ACAD 004225108 Health Care 2,659,140 $52,544,606.40 3.64%
Sarepta Therapeutics, Inc. SRPT 803607100 Health Care 395,134 $51,912,704.92 3.60%
FibroGen, Inc. FGEN 31572Q808 Health Care 2,575,293 $51,505,860.00 3.57%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Health Care 166,068 $49,646,028.60 3.44%
Alkermes Plc ALKS G01767105 Health Care 1,856,218 $49,431,085.34 3.43%
Gilead Sciences, Inc. GILD 375558103 Health Care 619,857 $49,253,837.22 3.41%
Mettler-Toledo International Inc. MTD 592688105 Health Care 32,951 $48,593,498.72 3.37%
Biogen Inc. BIIB 09062X103 Health Care 180,055 $48,238,535.05 3.34%
Exact Sciences Corporation EXAS 30063P105 Health Care 754,131 $47,842,070.64 3.32%
BioNTech SE (ADR) BNTX 09075V102 Health Care 360,350 $47,595,028.00 3.30%
Ultragenyx Pharmaceutical Inc. RARE 90400D108 Health Care 1,213,546 $47,328,294.00 3.28%
QIAGEN N.V. QGEN N72482123 Health Care 1,020,515 $46,780,407.60 3.24%
Amgen Inc. AMGN 031162100 Health Care 195,466 $45,879,779.52 3.18%
Bio-Techne Corporation TECH 09073M104 Health Care 631,652 $45,832,669.12 3.18%
Incyte Corporation INCY 45337C102 Health Care 618,442 $45,900,765.24 3.18%
Genmab A/S (ADR) GMAB 372303206 Health Care 1,273,938 $45,810,810.48 3.17%
Ionis Pharmaceuticals, Inc. IONS 462222100 Health Care 1,262,374 $44,940,514.40 3.11%
Neurocrine Biosciences, Inc. NBIX 64125C109 Health Care 462,054 $44,916,269.34 3.11%
United Therapeutics Corporation UTHR 91307C102 Health Care 196,616 $44,260,227.76 3.07%
IQVIA Holdings Inc. IQV 46266C105 Health Care 230,108 $44,137,015.48 3.06%
BioMarin Pharmaceutical Inc. BMRN 09061G101 Health Care 464,599 $42,901,071.66 2.97%
Alnylam Pharmaceuticals, Inc. ALNY 02043Q107 Health Care 224,056 $42,014,981.12 2.91%
Agios Pharmaceuticals, Inc. AGIO 00847X104 Health Care 1,827,214 $41,532,574.22 2.88%
Moderna, Inc. MRNA 60770K107 Health Care 265,256 $40,987,357.12 2.84%
Charles River Laboratories International, Inc. CRL 159864107 Health Care 211,598 $40,751,658.82 2.82%
Grifols, S.A. (ADR) GRFS 398438408 Health Care 5,592,865 $37,248,480.90 2.58%
US Dollar $USD Other 1,071,902 $1,071,902.35 0.07%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.


 
The information presented is not intended to constitute an investment recommendation for, or advice to, any specific person. By providing this information, First Trust is not undertaking to give advice in any fiduciary capacity within the meaning of ERISA, the Internal Revenue Code or any other regulatory framework. Financial professionals are responsible for evaluating investment risks independently and for exercising independent judgment in determining whether investments are appropriate for their clients.
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