First Trust Health Care AlphaDEX® Fund (FXH)
Holdings of the Fund as of 12/5/2023

Total Number of Holdings (excluding cash): 84

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
Cardinal Health, Inc. CAH 14149Y108 Pharmaceuticals and Biotechnology 281,085 $30,115,446.90 2.45%
Medpace Holdings, Inc. MEDP 58506Q109 Pharmaceuticals and Biotechnology 100,788 $27,899,126.28 2.27%
Molina Healthcare, Inc. MOH 60855R100 Health Care Providers 74,427 $27,314,709.00 2.22%
Centene Corporation CNC 15135B101 Health Care Providers 354,294 $26,575,592.94 2.16%
Universal Health Services, Inc. (Class B) UHS 913903100 Health Care Providers 194,097 $26,418,542.67 2.15%
United Therapeutics Corporation UTHR 91307C102 Pharmaceuticals and Biotechnology 108,043 $25,963,813.33 2.11%
Humana Inc. HUM 444859102 Health Care Providers 50,160 $25,097,556.00 2.04%
Seagen Inc. SGEN 81181C104 Pharmaceuticals and Biotechnology 115,031 $24,827,140.73 2.02%
Exelixis, Inc. EXEL 30161Q104 Pharmaceuticals and Biotechnology 1,116,877 $24,426,099.99 1.99%
Encompass Health Corporation EHC 29261A100 Health Care Providers 363,368 $23,789,702.96 1.93%
Viatris Inc. VTRS 92556V106 Pharmaceuticals and Biotechnology 2,475,026 $23,784,999.86 1.93%
Premier, Inc. (Class A) PINC 74051N102 Health Care Providers 1,135,059 $23,529,773.07 1.91%
Teleflex Incorporated TFX 879369106 Medical Equipment and Services 99,399 $22,619,236.44 1.84%
Elanco Animal Health Incorporated ELAN 28414H103 Pharmaceuticals and Biotechnology 1,736,923 $22,336,829.78 1.82%
The Cigna Group CI 125523100 Health Care Providers 85,307 $21,990,438.46 1.79%
Biogen Inc. BIIB 09062X103 Pharmaceuticals and Biotechnology 94,953 $21,798,360.21 1.77%
DaVita Inc. DVA 23918K108 Health Care Providers 206,527 $21,604,789.47 1.76%
Elevance Health Inc. ELV 036752103 Health Care Providers 44,838 $21,614,157.90 1.76%
Quest Diagnostics Incorporated DGX 74834L100 Medical Equipment and Services 160,209 $21,610,592.01 1.76%
Eli Lilly and Company LLY 532457108 Pharmaceuticals and Biotechnology 36,346 $21,376,899.90 1.74%
ICON Plc ICLR G4705A100 Medical Equipment and Services 79,282 $21,366,499.00 1.74%
Pfizer Inc. PFE 717081103 Pharmaceuticals and Biotechnology 735,718 $21,402,036.62 1.74%
Integra LifeSciences Holdings Corporation IART 457985208 Medical Equipment and Services 511,207 $21,220,202.57 1.73%
UnitedHealth Group Incorporated UNH 91324P102 Health Care Providers 38,721 $21,306,617.46 1.73%
Bristol-Myers Squibb Company BMY 110122108 Pharmaceuticals and Biotechnology 420,465 $21,119,956.95 1.72%
Laboratory Corporation of America Holdings LH 50540R409 Medical Equipment and Services 97,105 $21,073,727.10 1.71%
Gilead Sciences, Inc. GILD 375558103 Pharmaceuticals and Biotechnology 260,515 $20,585,895.30 1.67%
Neurocrine Biosciences, Inc. NBIX 64125C109 Pharmaceuticals and Biotechnology 173,538 $20,571,194.52 1.67%
Roivant Sciences Ltd. ROIV G76279101 Pharmaceuticals and Biotechnology 2,089,363 $20,517,544.66 1.67%
Charles River Laboratories International, Inc. CRL 159864107 Pharmaceuticals and Biotechnology 99,617 $19,758,035.78 1.61%
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Pharmaceuticals and Biotechnology 23,723 $19,474,210.70 1.58%
Globus Medical, Inc. (Class A) GMED 379577208 Medical Equipment and Services 393,213 $17,828,277.42 1.45%
QuidelOrtho Corporation QDEL 219798105 Medical Equipment and Services 267,293 $17,758,946.92 1.44%
Envista Holdings Corporation NVST 29415F104 Medical Equipment and Services 700,251 $16,595,948.70 1.35%
Tenet Healthcare Corporation THC 88033G407 Health Care Providers 222,223 $15,595,610.14 1.27%
Acadia Healthcare Company, Inc. ACHC 00404A109 Health Care Providers 208,253 $15,454,455.13 1.26%
Intuitive Surgical, Inc. ISRG 46120E602 Medical Equipment and Services 50,095 $15,505,404.40 1.26%
Zimmer Biomet Holdings, Inc. ZBH 98956P102 Medical Equipment and Services 130,478 $15,111,961.96 1.23%
HCA Healthcare, Inc. HCA 40412C101 Health Care Providers 59,527 $15,031,162.77 1.22%
QIAGEN N.V. QGEN N72482123 Medical Equipment and Services 361,537 $14,848,324.59 1.21%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Pharmaceuticals and Biotechnology 42,108 $14,912,548.20 1.21%
Amgen Inc. AMGN 031162100 Pharmaceuticals and Biotechnology 54,481 $14,757,268.47 1.20%
Medtronic Plc MDT G5960L103 Medical Equipment and Services 186,858 $14,728,147.56 1.20%
Perrigo Company Plc PRGO G97822103 Pharmaceuticals and Biotechnology 458,287 $14,165,651.17 1.15%
Exact Sciences Corporation EXAS 30063P105 Pharmaceuticals and Biotechnology 214,633 $13,901,779.41 1.13%
Henry Schein, Inc. HSIC 806407102 Medical Equipment and Services 197,203 $13,780,545.64 1.12%
West Pharmaceutical Services, Inc. WST 955306105 Medical Equipment and Services 39,024 $13,403,573.28 1.09%
Veeva Systems Inc. (Class A) VEEV 922475108 Health Care Providers 71,970 $12,807,781.20 1.04%
Agilent Technologies, Inc. A 00846U101 Medical Equipment and Services 87,297 $11,163,540.36 0.91%
Doximity, Inc. (Class A) DOCS 26622P107 Health Care Providers 460,015 $10,943,756.85 0.89%
Ionis Pharmaceuticals, Inc. IONS 462222100 Pharmaceuticals and Biotechnology 215,200 $10,760,000.00 0.88%
Abbott Laboratories ABT 002824100 Medical Equipment and Services 100,790 $10,517,436.50 0.86%
BioMarin Pharmaceutical Inc. BMRN 09061G101 Pharmaceuticals and Biotechnology 110,325 $10,327,523.25 0.84%
Stryker Corporation SYK 863667101 Medical Equipment and Services 35,721 $10,377,307.71 0.84%
Zoetis Inc. ZTS 98978V103 Pharmaceuticals and Biotechnology 56,107 $10,079,622.55 0.82%
Danaher Corporation DHR 235851102 Medical Equipment and Services 44,388 $9,740,502.72 0.79%
Hologic, Inc. HOLX 436440101 Medical Equipment and Services 140,655 $9,741,765.30 0.79%
Organon & Co. OGN 68622V106 Pharmaceuticals and Biotechnology 843,448 $9,353,838.32 0.76%
Bio-Techne Corporation TECH 09073M104 Medical Equipment and Services 143,404 $9,232,349.52 0.75%
Incyte Corporation INCY 45337C102 Pharmaceuticals and Biotechnology 168,972 $9,263,045.04 0.75%
Jazz Pharmaceuticals Plc JAZZ G50871105 Pharmaceuticals and Biotechnology 75,413 $9,161,925.37 0.75%
Revvity, Inc. RVTY 714046109 Medical Equipment and Services 88,179 $7,878,793.65 0.64%
Maravai LifeSciences Holdings, Inc. (Class A) MRVI 56600D107 Pharmaceuticals and Biotechnology 1,464,226 $7,628,617.46 0.62%
Moderna, Inc. MRNA 60770K107 Pharmaceuticals and Biotechnology 94,506 $7,397,929.68 0.60%
ICU Medical, Inc. ICUI 44930G107 Medical Equipment and Services 82,023 $7,292,664.93 0.59%
Sarepta Therapeutics, Inc. SRPT 803607100 Pharmaceuticals and Biotechnology 80,528 $7,097,737.92 0.58%
Natera, Inc. NTRA 632307104 Medical Equipment and Services 110,300 $6,428,284.00 0.52%
agilon health, inc. AGL 00857U107 Health Care Providers 549,634 $6,073,455.70 0.49%
Azenta Inc. AZTA 114340102 Medical Equipment and Services 97,246 $5,538,159.70 0.45%
Chemed Corporation CHE 16359R103 Health Care Providers 9,391 $5,415,320.15 0.44%
IQVIA Holdings Inc. IQV 46266C105 Health Care Providers 24,807 $5,316,388.17 0.43%
Royalty Pharma Plc (Class A) RPRX G7709Q104 Pharmaceuticals and Biotechnology 179,836 $5,116,334.20 0.42%
The Cooper Companies, Inc. COO 216648402 Medical Equipment and Services 15,348 $5,146,030.92 0.42%
Merck & Co., Inc. MRK 58933Y105 Pharmaceuticals and Biotechnology 47,409 $5,036,258.07 0.41%
Certara, Inc. CERT 15687V109 Medical Equipment and Services 335,677 $4,978,089.91 0.40%
Johnson & Johnson JNJ 478160104 Pharmaceuticals and Biotechnology 31,337 $4,968,481.35 0.40%
Avantor, Inc. AVTR 05352A100 Medical Equipment and Services 231,535 $4,795,089.85 0.39%
Repligen Corporation RGEN 759916109 Medical Equipment and Services 30,695 $4,743,912.25 0.39%
Thermo Fisher Scientific Inc. TMO 883556102 Medical Equipment and Services 9,643 $4,740,498.80 0.39%
AbbVie Inc. ABBV 00287Y109 Pharmaceuticals and Biotechnology 32,744 $4,733,800.08 0.38%
Alnylam Pharmaceuticals, Inc. ALNY 02043Q107 Pharmaceuticals and Biotechnology 27,559 $4,695,226.83 0.38%
Enovis Corp. ENOV 194014502 Medical Equipment and Services 92,561 $4,509,571.92 0.37%
Becton, Dickinson and Company BDX 075887109 Medical Equipment and Services 18,878 $4,409,900.80 0.36%
Catalent, Inc. CTLT 148806102 Pharmaceuticals and Biotechnology 107,198 $4,171,074.18 0.34%
US Dollar $USD Other 1,628,133 $1,628,132.93 0.13%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.