First Trust Health Care AlphaDEX® Fund (FXH)
Holdings of the Fund as of 1/16/2020

Total Number of Holdings (excluding cash): 77

Security Name Identifier Classification Shares / Quantity Market Value Weighting Descending sort
Exelixis, Inc. EXEL Biotechnology 1,430,657 $29,242,629.08 2.48%
Envista Holdings Corporation NVST Health Care Equipment & Supplies 850,479 $27,164,299.26 2.30%
DexCom, Inc. DXCM Health Care Equipment & Supplies 115,242 $27,013,877.22 2.29%
Horizon Therapeutics Plc HZNP Pharmaceuticals 696,359 $26,663,586.11 2.26%
Alexion Pharmaceuticals, Inc. ALXN Biotechnology 233,086 $26,224,505.86 2.22%
Alnylam Pharmaceuticals, Inc. ALNY Biotechnology 218,877 $26,120,781.18 2.21%
Centene Corporation CNC Health Care Providers & Services 400,957 $26,114,329.41 2.21%
Cigna Corporation CI Health Care Providers & Services 123,272 $26,004,228.40 2.20%
UnitedHealth Group Incorporated UNH Health Care Providers & Services 85,747 $25,787,552.78 2.19%
WellCare Health Plans, Inc. WCG Health Care Providers & Services 76,339 $25,865,943.37 2.19%
Jazz Pharmaceuticals Plc JAZZ Pharmaceuticals 168,867 $25,598,548.53 2.17%
Humana Inc. HUM Health Care Providers & Services 68,776 $25,249,732.88 2.14%
Neurocrine Biosciences, Inc. NBIX Biotechnology 234,515 $24,935,979.95 2.11%
Biogen Inc. BIIB Biotechnology 84,952 $24,308,165.28 2.06%
Seattle Genetics, Inc. SGEN Biotechnology 220,621 $23,752,056.86 2.01%
Perrigo Company Plc PRGO Pharmaceuticals 390,370 $23,230,918.70 1.97%
Insulet Corporation PODD Health Care Equipment & Supplies 117,796 $22,553,222.16 1.91%
Mylan N.V. MYL Pharmaceuticals 1,003,311 $22,042,742.67 1.87%
Chemed Corporation CHE Health Care Providers & Services 45,910 $21,726,907.50 1.84%
Vertex Pharmaceuticals Incorporated VRTX Biotechnology 92,106 $21,690,963.00 1.84%
Bruker Corporation BRKR Life Sciences Tools & Services 395,657 $21,361,521.43 1.81%
Charles River Laboratories International, Inc. CRL Life Sciences Tools & Services 132,014 $21,116,959.44 1.79%
Bristol-Myers Squibb Company BMY Pharmaceuticals 314,169 $20,980,205.82 1.78%
Molina Healthcare, Inc. MOH Health Care Providers & Services 148,624 $20,935,176.64 1.77%
Pfizer Inc. PFE Pharmaceuticals 514,716 $20,902,616.76 1.77%
ResMed Inc. RMD Health Care Equipment & Supplies 130,132 $20,916,116.36 1.77%
Edwards Lifesciences Corporation EW Health Care Equipment & Supplies 86,445 $20,624,048.10 1.75%
Anthem, Inc. ANTM Health Care Providers & Services 66,771 $20,368,493.55 1.73%
Universal Health Services, Inc. (Class B) UHS Health Care Providers & Services 140,572 $20,233,933.68 1.72%
HCA Healthcare, Inc. HCA Health Care Providers & Services 136,437 $20,161,295.49 1.71%
Encompass Health Corporation EHC Health Care Providers & Services 204,701 $16,427,255.25 1.39%
Guardant Health, Inc. GH Health Care Providers & Services 181,465 $15,125,107.75 1.28%
West Pharmaceutical Services, Inc. WST Health Care Equipment & Supplies 94,324 $14,937,148.64 1.27%
Laboratory Corporation of America Holdings LH Health Care Providers & Services 83,820 $14,898,166.80 1.26%
Varian Medical Systems, Inc. VAR Health Care Equipment & Supplies 99,849 $14,852,538.75 1.26%
Zoetis Inc. ZTS Pharmaceuticals 107,137 $14,917,755.88 1.26%
Thermo Fisher Scientific Inc. TMO Life Sciences Tools & Services 43,646 $14,697,354.04 1.25%
Align Technology, Inc. ALGN Health Care Equipment & Supplies 50,816 $14,484,084.48 1.23%
Regeneron Pharmaceuticals, Inc. REGN Biotechnology 37,763 $14,560,279.91 1.23%
Teleflex Incorporated TFX Health Care Equipment & Supplies 37,666 $14,478,057.08 1.23%
Quest Diagnostics Incorporated DGX Health Care Providers & Services 132,780 $14,222,065.80 1.21%
Amgen Inc. AMGN Biotechnology 58,819 $14,145,969.50 1.20%
Bio-Techne Corporation TECH Life Sciences Tools & Services 64,597 $14,173,227.77 1.20%
Penumbra, Inc. PEN Health Care Equipment & Supplies 86,318 $13,847,996.74 1.17%
PRA Health Sciences, Inc. PRAH Life Sciences Tools & Services 127,573 $13,558,458.44 1.15%
Incyte Corporation INCY Biotechnology 162,388 $13,091,720.56 1.11%
McKesson Corporation MCK Health Care Providers & Services 72,898 $11,391,041.48 0.97%
AmerisourceBergen Corporation ABC Health Care Providers & Services 118,600 $10,847,156.00 0.92%
Baxter International Inc. BAX Health Care Equipment & Supplies 120,584 $10,851,354.16 0.92%
Eli Lilly and Company LLY Pharmaceuticals 76,720 $10,850,509.60 0.92%
Masimo Corporation MASI Health Care Equipment & Supplies 63,795 $10,834,304.85 0.92%
Agilent Technologies, Inc. A Life Sciences Tools & Services 118,195 $10,573,724.70 0.90%
Danaher Corporation DHR Health Care Equipment & Supplies 65,699 $10,611,045.49 0.90%
DaVita Inc. DVA Health Care Providers & Services 134,389 $10,615,387.11 0.90%
PerkinElmer, Inc. PKI Life Sciences Tools & Services 103,843 $10,510,988.46 0.89%
Bio-Rad Laboratories, Inc. (Class A) BIO Life Sciences Tools & Services 27,250 $10,346,825.00 0.88%
Hill-Rom Holdings, Inc. HRC Health Care Equipment & Supplies 88,816 $10,332,853.44 0.88%
Intuitive Surgical, Inc. ISRG Health Care Equipment & Supplies 17,058 $10,205,630.82 0.87%
AbbVie Inc. ABBV Biotechnology 113,883 $10,165,196.58 0.86%
Merck & Co., Inc. MRK Pharmaceuticals 110,865 $10,108,670.70 0.86%
Steris Plc STE Health Care Equipment & Supplies 66,155 $10,196,470.15 0.86%
The Cooper Companies, Inc. COO Health Care Equipment & Supplies 14,713 $5,135,719.78 0.44%
Agios Pharmaceuticals, Inc. AGIO Biotechnology 98,984 $5,102,625.20 0.43%
Moderna, Inc. MRNA Biotechnology 241,643 $5,076,919.43 0.43%
Hologic, Inc. HOLX Health Care Equipment & Supplies 90,530 $4,908,536.60 0.42%
IQVIA Holdings Inc. IQV Life Sciences Tools & Services 30,592 $4,924,394.24 0.42%
Medtronic Plc MDT Health Care Equipment & Supplies 41,663 $4,952,064.18 0.42%
Becton, Dickinson and Company BDX Health Care Equipment & Supplies 17,380 $4,812,000.60 0.41%
Cerner Corporation CERN Health Care Technology 64,402 $4,867,503.16 0.41%
Johnson & Johnson JNJ Pharmaceuticals 32,402 $4,801,976.40 0.41%
ICU Medical, Inc. ICUI Health Care Equipment & Supplies 25,258 $4,759,617.52 0.40%
Sarepta Therapeutics, Inc. SRPT Biotechnology 36,627 $4,772,498.10 0.40%
Stryker Corporation SYK Health Care Equipment & Supplies 22,515 $4,715,991.90 0.40%
Exact Sciences Corporation EXAS Biotechnology 51,110 $4,588,655.80 0.39%
Gilead Sciences, Inc. GILD Biotechnology 72,740 $4,597,168.00 0.39%
Premier, Inc. (Class A) PINC Health Care Providers & Services 124,777 $4,621,740.08 0.39%
Boston Scientific Corporation BSX Health Care Equipment & Supplies 104,523 $4,515,393.60 0.38%
US Dollar $USD Other 2,698,372 $2,698,371.50 0.23%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.