First Trust Health Care AlphaDEX® Fund (FXH)
Holdings of the Fund as of 10/22/2026

Total Number of Holdings (excluding cash): 72

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
The Cigna Group CI 125523100 Health Care Providers 96,615 $30,518,746.20 2.64%
Centene Corporation CNC 15135B101 Health Care Providers 422,780 $30,118,847.20 2.61%
Halozyme Therapeutics, Inc. HALO 40637H109 Pharmaceuticals and Biotechnology 237,890 $29,626,820.60 2.57%
Zimmer Biomet Holdings, Inc. ZBH 98956P102 Medical Equipment and Services 295,660 $29,214,164.60 2.53%
Globus Medical, Inc. (Class A) GMED 379577208 Medical Equipment and Services 350,643 $28,633,507.38 2.48%
Universal Health Services, Inc. (Class B) UHS 913903100 Health Care Providers 150,712 $28,353,448.56 2.46%
Medpace Holdings, Inc. MEDP 58506Q109 Pharmaceuticals and Biotechnology 42,076 $27,516,020.96 2.38%
Caris Life Sciences, Inc. CAI 142152107 Pharmaceuticals and Biotechnology 857,433 $27,189,200.43 2.36%
Solventum Corporation SOLV 83444M101 Medical Equipment and Services 297,938 $26,054,678.10 2.26%
Natera, Inc. NTRA 632307104 Medical Equipment and Services 63,544 $25,504,655.28 2.21%
Zoetis Inc. ZTS 98978V103 Pharmaceuticals and Biotechnology 300,884 $24,672,488.00 2.14%
Corcept Therapeutics Inc. CORT 218352102 Pharmaceuticals and Biotechnology 227,918 $24,501,185.00 2.12%
Guardant Health, Inc. GH 40131M109 Pharmaceuticals and Biotechnology 147,250 $23,992,915.00 2.08%
DexCom, Inc. DXCM 252131107 Medical Equipment and Services 304,360 $23,837,475.20 2.07%
Eli Lilly and Company LLY 532457108 Pharmaceuticals and Biotechnology 18,161 $23,730,797.09 2.06%
Exelixis, Inc. EXEL 30161Q104 Pharmaceuticals and Biotechnology 359,712 $23,492,790.72 2.04%
GE HealthCare Technologies Inc. GEHC 36266G107 Medical Equipment and Services 321,409 $22,955,030.78 1.99%
The Cooper Companies, Inc. COO 216648501 Medical Equipment and Services 371,673 $22,913,640.45 1.99%
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Pharmaceuticals and Biotechnology 27,708 $22,695,345.72 1.97%
United Therapeutics Corporation UTHR 91307C102 Pharmaceuticals and Biotechnology 38,775 $22,675,232.25 1.96%
Medtronic Plc MDT G5960L103 Medical Equipment and Services 233,218 $22,526,526.62 1.95%
Amgen Inc. AMGN 031162100 Pharmaceuticals and Biotechnology 49,846 $22,295,118.88 1.93%
Tenet Healthcare Corporation THC 88033G407 Health Care Providers 82,217 $22,250,386.71 1.93%
Boston Scientific Corporation BSX 101137107 Medical Equipment and Services 481,344 $22,146,637.44 1.92%
Bristol-Myers Squibb Company BMY 110122108 Pharmaceuticals and Biotechnology 336,711 $21,212,793.00 1.84%
Tempus AI, Inc. (Class A) TEM 88023B103 Pharmaceuticals and Biotechnology 320,678 $20,462,463.18 1.77%
Incyte Corporation INCY 45337C102 Pharmaceuticals and Biotechnology 173,141 $20,245,377.13 1.75%
Jazz Pharmaceuticals Plc JAZZ G50871105 Pharmaceuticals and Biotechnology 90,750 $19,479,487.50 1.69%
Elevance Health Inc. ELV 036752103 Health Care Providers 37,825 $16,842,716.00 1.46%
QIAGEN N.V. QGEN N72482156 Pharmaceuticals and Biotechnology 336,091 $16,878,490.02 1.46%
ResMed Inc. RMD 761152107 Medical Equipment and Services 66,517 $16,832,792.02 1.46%
Steris Plc STE G8473T100 Medical Equipment and Services 70,034 $16,263,295.48 1.41%
HCA Healthcare, Inc. HCA 40412C101 Health Care Providers 34,464 $16,105,371.84 1.40%
AbbVie Inc. ABBV 00287Y109 Pharmaceuticals and Biotechnology 56,221 $16,033,666.99 1.39%
Align Technology, Inc. ALGN 016255101 Medical Equipment and Services 101,185 $15,735,279.35 1.36%
Ascendis Pharma A/S ASND K08588103 Pharmaceuticals and Biotechnology 64,554 $15,685,976.46 1.36%
DaVita Inc. DVA 23918K108 Health Care Providers 84,078 $15,646,915.80 1.36%
Labcorp Holdings Inc. LH 504922105 Medical Equipment and Services 47,737 $15,749,868.41 1.36%
Quest Diagnostics Incorporated DGX 74834L100 Medical Equipment and Services 63,105 $15,352,184.40 1.33%
Viatris Inc. VTRS 92556V106 Pharmaceuticals and Biotechnology 829,991 $15,338,233.68 1.33%
Encompass Health Corporation EHC 29261A100 Health Care Providers 121,060 $15,254,770.60 1.32%
Neurocrine Biosciences, Inc. NBIX 64125C109 Pharmaceuticals and Biotechnology 103,688 $14,857,453.52 1.29%
Revolution Medicines, Inc. RVMD 76155X100 Pharmaceuticals and Biotechnology 71,652 $13,448,363.88 1.17%
Doximity, Inc. (Class A) DOCS 26622P107 Health Care Providers 370,691 $12,484,872.88 1.08%
Becton, Dickinson and Company BDX 075887109 Medical Equipment and Services 58,690 $11,762,649.80 1.02%
Biogen Inc. BIIB 09062X103 Pharmaceuticals and Biotechnology 46,510 $11,806,098.40 1.02%
Pfizer Inc. PFE 717081103 Pharmaceuticals and Biotechnology 368,346 $11,205,085.32 0.97%
Abbott Laboratories ABT 002824100 Medical Equipment and Services 106,296 $10,896,402.96 0.94%
BridgeBio Pharma, Inc. BBIO 10806X102 Pharmaceuticals and Biotechnology 159,653 $10,875,562.36 0.94%
Chemed Corporation CHE 16359R103 Health Care Providers 20,800 $10,819,120.00 0.94%
The Ensign Group, Inc. ENSG 29358P101 Health Care Providers 61,080 $10,893,618.00 0.94%
Envista Holdings Corporation NVST 29415F104 Medical Equipment and Services 447,603 $10,729,043.91 0.93%
Henry Schein, Inc. HSIC 806407102 Medical Equipment and Services 125,110 $10,759,460.00 0.93%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Pharmaceuticals and Biotechnology 20,094 $10,753,705.98 0.93%
Madrigal Pharmaceuticals, Inc. MDGL 558868105 Pharmaceuticals and Biotechnology 20,848 $9,451,232.32 0.82%
Arrowhead Pharmaceuticals, Inc. ARWR 04280A100 Pharmaceuticals and Biotechnology 160,507 $9,367,188.52 0.81%
Axsome Therapeutics, Inc. AXSM 05464T104 Pharmaceuticals and Biotechnology 56,974 $8,891,932.18 0.77%
UnitedHealth Group Incorporated UNH 91324P102 Health Care Providers 13,355 $5,675,607.90 0.49%
Veeva Systems Inc. (Class A) VEEV 922475108 Health Care Providers 17,172 $5,538,828.60 0.48%
Humana Inc. HUM 444859102 Health Care Providers 12,848 $5,408,622.56 0.47%
Stryker Corporation SYK 863667101 Medical Equipment and Services 17,804 $5,467,252.32 0.47%
IDEXX Laboratories, Inc. IDXX 45168D104 Medical Equipment and Services 9,386 $5,319,609.36 0.46%
Intuitive Surgical, Inc. ISRG 46120E602 Medical Equipment and Services 12,059 $5,352,387.15 0.46%
West Pharmaceutical Services, Inc. WST 955306105 Medical Equipment and Services 13,224 $5,210,652.72 0.45%
Danaher Corporation DHR 235851102 Medical Equipment and Services 22,128 $5,083,908.00 0.44%
Agilent Technologies, Inc. A 00846U101 Medical Equipment and Services 28,454 $4,947,866.06 0.43%
Elanco Animal Health Incorporated ELAN 28414H103 Pharmaceuticals and Biotechnology 218,956 $4,968,111.64 0.43%
Johnson & Johnson JNJ 478160104 Pharmaceuticals and Biotechnology 18,515 $4,954,799.15 0.43%
Medline Inc. (Class A) MDLN 58507V107 Medical Equipment and Services 141,282 $4,927,916.16 0.43%
Thermo Fisher Scientific Inc. TMO 883556102 Medical Equipment and Services 7,262 $4,913,033.48 0.43%
Bio-Rad Laboratories, Inc. (Class A) BIO 090572207 Medical Equipment and Services 12,978 $4,717,503.00 0.41%
Insmed Incorporated INSM 457669307 Pharmaceuticals and Biotechnology 42,952 $4,083,017.12 0.35%
US Dollar $USD Other 2,220,516 $2,220,515.83 0.19%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.