First Trust Health Care AlphaDEX® Fund (FXH)
Holdings of the Fund as of 8/20/2026

Total Number of Holdings (excluding cash): 73

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Pharmaceuticals and Biotechnology 39,908 $32,989,549.12 2.85%
Natera, Inc. NTRA 632307104 Medical Equipment and Services 91,664 $29,776,133.76 2.57%
Universal Health Services, Inc. (Class B) UHS 913903100 Health Care Providers 167,334 $28,927,028.58 2.50%
Boston Scientific Corporation BSX 101137107 Medical Equipment and Services 582,979 $28,781,673.23 2.49%
Pfizer Inc. PFE 717081103 Pharmaceuticals and Biotechnology 1,033,286 $28,715,017.94 2.48%
Solventum Corporation SOLV 83444M101 Medical Equipment and Services 322,505 $28,577,168.05 2.47%
Zimmer Biomet Holdings, Inc. ZBH 98956P102 Medical Equipment and Services 289,022 $28,604,507.34 2.47%
Guardant Health, Inc. GH 40131M109 Pharmaceuticals and Biotechnology 165,848 $27,842,562.24 2.41%
Tenet Healthcare Corporation THC 88033G407 Health Care Providers 99,306 $27,070,815.60 2.34%
Globus Medical, Inc. (Class A) GMED 379577208 Medical Equipment and Services 314,911 $26,978,425.37 2.33%
Corcept Therapeutics Inc. CORT 218352102 Pharmaceuticals and Biotechnology 213,664 $25,864,027.20 2.24%
Halozyme Therapeutics, Inc. HALO 40637H109 Pharmaceuticals and Biotechnology 237,360 $25,188,643.20 2.18%
Centene Corporation CNC 15135B101 Health Care Providers 387,627 $24,862,395.78 2.15%
The Cigna Group CI 125523100 Health Care Providers 90,259 $24,767,972.19 2.14%
Encompass Health Corporation EHC 29261A100 Health Care Providers 183,791 $22,222,169.81 1.92%
Medtronic Plc MDT G5960L103 Medical Equipment and Services 237,485 $21,919,865.50 1.89%
ResMed Inc. RMD 761152107 Medical Equipment and Services 95,331 $21,777,413.64 1.88%
QIAGEN N.V. QGEN N72482156 Pharmaceuticals and Biotechnology 475,138 $21,333,696.21 1.84%
Axsome Therapeutics, Inc. AXSM 05464T104 Pharmaceuticals and Biotechnology 101,658 $21,147,913.74 1.83%
Incyte Corporation INCY 45337C102 Pharmaceuticals and Biotechnology 163,882 $20,849,068.04 1.80%
Medline Inc. (Class A) MDLN 58507V107 Medical Equipment and Services 630,873 $20,553,842.34 1.78%
Arrowhead Pharmaceuticals, Inc. ARWR 04280A100 Pharmaceuticals and Biotechnology 227,919 $19,936,074.93 1.72%
DaVita Inc. DVA 23918K108 Health Care Providers 111,831 $19,597,264.44 1.69%
Zoetis Inc. ZTS 98978V103 Pharmaceuticals and Biotechnology 258,527 $19,394,695.54 1.68%
Eli Lilly and Company LLY 532457108 Pharmaceuticals and Biotechnology 15,495 $19,281,978.00 1.67%
Elevance Health Inc. ELV 036752103 Health Care Providers 48,043 $19,038,480.04 1.65%
Doximity, Inc. (Class A) DOCS 26622P107 Health Care Providers 719,814 $18,671,975.16 1.61%
Becton, Dickinson and Company BDX 075887109 Medical Equipment and Services 98,648 $18,508,337.76 1.60%
United Therapeutics Corporation UTHR 91307C102 Pharmaceuticals and Biotechnology 34,285 $17,862,485.00 1.54%
Ascendis Pharma A/S ASND K08588103 Pharmaceuticals and Biotechnology 69,659 $17,749,809.79 1.53%
Labcorp Holdings Inc. LH 504922105 Medical Equipment and Services 53,315 $17,743,765.15 1.53%
GE HealthCare Technologies Inc. GEHC 36266G107 Medical Equipment and Services 233,226 $17,272,717.56 1.49%
Medpace Holdings, Inc. MEDP 58506Q109 Pharmaceuticals and Biotechnology 28,190 $17,270,321.60 1.49%
Bristol-Myers Squibb Company BMY 110122108 Pharmaceuticals and Biotechnology 259,096 $16,963,015.12 1.47%
Quest Diagnostics Incorporated DGX 74834L100 Medical Equipment and Services 70,434 $16,995,724.20 1.47%
Gilead Sciences, Inc. GILD 375558103 Pharmaceuticals and Biotechnology 118,164 $16,949,444.16 1.46%
Neurocrine Biosciences, Inc. NBIX 64125C109 Pharmaceuticals and Biotechnology 110,231 $16,857,626.83 1.46%
Revolution Medicines, Inc. RVMD 76155X100 Pharmaceuticals and Biotechnology 79,717 $16,878,879.04 1.46%
Steris Plc STE G8473T100 Medical Equipment and Services 70,900 $16,713,966.00 1.44%
Viatris Inc. VTRS 92556V106 Pharmaceuticals and Biotechnology 940,103 $15,154,460.36 1.31%
Biogen Inc. BIIB 09062X103 Pharmaceuticals and Biotechnology 69,091 $14,809,655.85 1.28%
Exelixis, Inc. EXEL 30161Q104 Pharmaceuticals and Biotechnology 274,377 $14,731,301.13 1.27%
Veeva Systems Inc. (Class A) VEEV 922475108 Health Care Providers 52,347 $13,114,493.91 1.13%
IQVIA Holdings Inc. IQV 46266C105 Health Care Providers 48,077 $12,310,115.85 1.06%
Abbott Laboratories ABT 002824100 Medical Equipment and Services 102,374 $11,684,968.36 1.01%
Thermo Fisher Scientific Inc. TMO 883556102 Medical Equipment and Services 18,527 $11,626,618.85 1.00%
Ionis Pharmaceuticals, Inc. IONS 462222100 Pharmaceuticals and Biotechnology 188,278 $11,063,215.28 0.96%
Agilent Technologies, Inc. A 00846U101 Medical Equipment and Services 69,929 $10,929,902.70 0.94%
Chemed Corporation CHE 16359R103 Health Care Providers 19,941 $10,666,042.08 0.92%
Tempus AI, Inc. (Class A) TEM 88023B103 Pharmaceuticals and Biotechnology 160,352 $10,687,460.80 0.92%
BridgeBio Pharma, Inc. BBIO 10806X102 Pharmaceuticals and Biotechnology 124,720 $10,344,276.80 0.89%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Pharmaceuticals and Biotechnology 18,699 $10,102,321.74 0.87%
Henry Schein, Inc. HSIC 806407102 Medical Equipment and Services 111,221 $9,838,609.66 0.85%
AbbVie Inc. ABBV 00287Y109 Pharmaceuticals and Biotechnology 36,909 $9,663,883.47 0.84%
HCA Healthcare, Inc. HCA 40412C101 Health Care Providers 23,829 $9,681,007.83 0.84%
Organon & Co. OGN 68622V106 Pharmaceuticals and Biotechnology 686,052 $9,426,354.48 0.81%
Madrigal Pharmaceuticals, Inc. MDGL 558868105 Pharmaceuticals and Biotechnology 17,300 $8,980,257.00 0.78%
Align Technology, Inc. ALGN 016255101 Medical Equipment and Services 55,071 $8,752,984.74 0.76%
DexCom, Inc. DXCM 252131107 Medical Equipment and Services 68,966 $6,222,112.52 0.54%
Bio-Rad Laboratories, Inc. (Class A) BIO 090572207 Medical Equipment and Services 15,813 $5,952,961.98 0.51%
Illumina, Inc. ILMN 452327109 Pharmaceuticals and Biotechnology 26,419 $5,633,587.56 0.49%
Amgen Inc. AMGN 031162100 Pharmaceuticals and Biotechnology 12,824 $5,562,153.52 0.48%
BioMarin Pharmaceutical Inc. BMRN 09061G101 Pharmaceuticals and Biotechnology 81,167 $5,493,382.56 0.47%
Merck & Co., Inc. MRK 58933Y105 Pharmaceuticals and Biotechnology 36,145 $5,385,243.55 0.47%
Danaher Corporation DHR 235851102 Medical Equipment and Services 24,384 $5,264,749.44 0.45%
Revvity, Inc. RVTY 714046109 Medical Equipment and Services 41,741 $5,181,310.33 0.45%
The Ensign Group, Inc. ENSG 29358P101 Health Care Providers 28,968 $5,209,894.80 0.45%
The Cooper Companies, Inc. COO 216648501 Medical Equipment and Services 64,763 $4,932,350.08 0.43%
IDEXX Laboratories, Inc. IDXX 45168D104 Medical Equipment and Services 8,823 $4,816,122.78 0.42%
Johnson & Johnson JNJ 478160104 Pharmaceuticals and Biotechnology 18,292 $4,890,732.04 0.42%
Stryker Corporation SYK 863667101 Medical Equipment and Services 14,748 $4,832,919.60 0.42%
Envista Holdings Corporation NVST 29415F104 Medical Equipment and Services 176,265 $4,746,816.45 0.41%
West Pharmaceutical Services, Inc. WST 955306105 Medical Equipment and Services 12,940 $4,577,783.80 0.40%
US Dollar $USD Other 2,454,863 $2,454,862.54 0.21%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.