First Trust Health Care AlphaDEX® Fund (FXH)
Holdings of the Fund as of 3/25/2026

Total Number of Holdings (excluding cash): 76

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
Acadia Healthcare Company, Inc. ACHC 00404A109 Health Care Providers 1,386,690 $33,710,433.90 4.02%
Pfizer Inc. PFE 717081103 Pharmaceuticals and Biotechnology 790,246 $21,557,910.88 2.57%
Biogen Inc. BIIB 09062X103 Pharmaceuticals and Biotechnology 111,808 $21,151,837.44 2.52%
HCA Healthcare, Inc. HCA 40412C101 Health Care Providers 42,148 $20,400,474.96 2.43%
Cardinal Health, Inc. CAH 14149Y108 Pharmaceuticals and Biotechnology 95,753 $20,233,566.43 2.41%
Incyte Corporation INCY 45337C102 Pharmaceuticals and Biotechnology 199,222 $18,374,245.06 2.19%
Ionis Pharmaceuticals, Inc. IONS 462222100 Pharmaceuticals and Biotechnology 248,731 $18,082,743.70 2.16%
Merck & Co., Inc. MRK 58933Y105 Pharmaceuticals and Biotechnology 149,550 $17,851,783.50 2.13%
United Therapeutics Corporation UTHR 91307C102 Pharmaceuticals and Biotechnology 32,307 $17,497,471.20 2.09%
Sarepta Therapeutics, Inc. SRPT 803607100 Pharmaceuticals and Biotechnology 731,491 $17,387,541.07 2.07%
Amgen Inc. AMGN 031162100 Pharmaceuticals and Biotechnology 48,094 $17,021,909.42 2.03%
Penumbra, Inc. PEN 70975L107 Medical Equipment and Services 50,631 $17,025,686.37 2.03%
Natera, Inc. NTRA 632307104 Medical Equipment and Services 85,892 $16,952,504.04 2.02%
Universal Health Services, Inc. (Class B) UHS 913903100 Health Care Providers 90,253 $16,852,040.16 2.01%
Eli Lilly and Company LLY 532457108 Pharmaceuticals and Biotechnology 18,310 $16,777,636.10 2.00%
Insmed Incorporated INSM 457669307 Pharmaceuticals and Biotechnology 113,061 $16,768,076.91 2.00%
Organon & Co. OGN 68622V106 Pharmaceuticals and Biotechnology 2,744,368 $16,740,644.80 2.00%
Medpace Holdings, Inc. MEDP 58506Q109 Pharmaceuticals and Biotechnology 35,035 $16,354,338.00 1.95%
Solventum Corporation SOLV 83444M101 Medical Equipment and Services 248,323 $16,051,598.72 1.91%
Molina Healthcare, Inc. MOH 60855R100 Health Care Providers 113,387 $15,856,038.08 1.89%
The Cigna Group CI 125523100 Health Care Providers 57,195 $15,463,240.20 1.84%
Zimmer Biomet Holdings, Inc. ZBH 98956P102 Medical Equipment and Services 175,064 $15,342,608.96 1.83%
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Pharmaceuticals and Biotechnology 20,394 $15,284,691.18 1.82%
IDEXX Laboratories, Inc. IDXX 45168D104 Medical Equipment and Services 23,268 $13,395,852.96 1.60%
Elevance Health Inc. ELV 036752103 Health Care Providers 44,906 $13,296,217.54 1.59%
Gilead Sciences, Inc. GILD 375558103 Pharmaceuticals and Biotechnology 96,189 $13,299,091.14 1.59%
Quest Diagnostics Incorporated DGX 74834L100 Medical Equipment and Services 68,036 $13,366,352.56 1.59%
Abbott Laboratories ABT 002824100 Medical Equipment and Services 125,642 $13,171,050.86 1.57%
Bristol-Myers Squibb Company BMY 110122108 Pharmaceuticals and Biotechnology 218,878 $12,900,669.32 1.54%
Labcorp Holdings Inc. LH 504922105 Medical Equipment and Services 47,059 $12,518,635.18 1.49%
Sotera Health Company SHC 83601L102 Medical Equipment and Services 892,387 $12,225,701.90 1.46%
Tenet Healthcare Corporation THC 88033G407 Health Care Providers 59,411 $11,884,576.44 1.42%
Globus Medical, Inc. (Class A) GMED 379577208 Medical Equipment and Services 135,223 $11,811,729.05 1.41%
Exelixis, Inc. EXEL 30161Q104 Pharmaceuticals and Biotechnology 269,366 $11,524,824.32 1.37%
Apellis Pharmaceuticals, Inc. APLS 03753U106 Pharmaceuticals and Biotechnology 626,660 $11,104,415.20 1.32%
BioMarin Pharmaceutical Inc. BMRN 09061G101 Pharmaceuticals and Biotechnology 198,658 $11,043,398.22 1.32%
Halozyme Therapeutics, Inc. HALO 40637H109 Pharmaceuticals and Biotechnology 175,427 $11,094,003.48 1.32%
Encompass Health Corporation EHC 29261A100 Health Care Providers 111,233 $10,992,045.06 1.31%
Perrigo Company Plc PRGO G97822103 Pharmaceuticals and Biotechnology 1,130,870 $10,958,130.30 1.31%
Repligen Corporation RGEN 759916109 Medical Equipment and Services 96,068 $10,982,493.76 1.31%
Neurocrine Biosciences, Inc. NBIX 64125C109 Pharmaceuticals and Biotechnology 83,242 $10,915,523.46 1.30%
QIAGEN N.V. QGEN N72482156 Medical Equipment and Services 262,097 $10,649,001.11 1.27%
Chemed Corporation CHE 16359R103 Health Care Providers 27,594 $10,320,707.88 1.23%
Intuitive Surgical, Inc. ISRG 46120E602 Medical Equipment and Services 20,845 $9,796,733.10 1.17%
Alnylam Pharmaceuticals, Inc. ALNY 02043Q107 Pharmaceuticals and Biotechnology 29,690 $9,759,103.00 1.16%
Johnson & Johnson JNJ 478160104 Pharmaceuticals and Biotechnology 38,032 $9,125,017.76 1.09%
Align Technology, Inc. ALGN 016255101 Medical Equipment and Services 50,406 $9,086,689.62 1.08%
Becton, Dickinson and Company BDX 075887109 Medical Equipment and Services 51,542 $8,157,552.34 0.97%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Pharmaceuticals and Biotechnology 17,361 $7,898,734.17 0.94%
Henry Schein, Inc. HSIC 806407102 Medical Equipment and Services 104,140 $7,732,395.00 0.92%
ResMed Inc. RMD 761152107 Medical Equipment and Services 32,677 $7,395,131.87 0.88%
Zoetis Inc. ZTS 98978V103 Pharmaceuticals and Biotechnology 62,556 $7,300,910.76 0.87%
Medtronic Plc MDT G5960L103 Medical Equipment and Services 81,937 $7,201,442.93 0.86%
AbbVie Inc. ABBV 00287Y109 Pharmaceuticals and Biotechnology 34,448 $7,136,936.64 0.85%
Revvity, Inc. RVTY 714046109 Medical Equipment and Services 81,353 $7,146,047.52 0.85%
GE HealthCare Technologies Inc. GEHC 36266G107 Medical Equipment and Services 95,962 $6,928,456.40 0.83%
UnitedHealth Group Incorporated UNH 91324P102 Health Care Providers 23,843 $6,450,723.65 0.77%
Waters Corporation WAT 941848103 Medical Equipment and Services 20,722 $6,264,675.05 0.75%
Certara, Inc. CERT 15687V109 Medical Equipment and Services 893,400 $5,449,740.00 0.65%
Humana Inc. HUM 444859102 Health Care Providers 30,730 $5,354,395.20 0.64%
Royalty Pharma Plc (Class A) RPRX G7709Q104 Pharmaceuticals and Biotechnology 95,482 $4,490,518.46 0.54%
Elanco Animal Health Incorporated ELAN 28414H103 Pharmaceuticals and Biotechnology 163,034 $4,157,367.00 0.50%
Edwards Lifesciences Corporation EW 28176E108 Medical Equipment and Services 43,279 $3,577,874.93 0.43%
Illumina, Inc. ILMN 452327109 Pharmaceuticals and Biotechnology 28,129 $3,549,879.80 0.42%
Viking Therapeutics, Inc. VKTX 92686J106 Pharmaceuticals and Biotechnology 104,874 $3,481,816.80 0.42%
Baxter International Inc. BAX 071813109 Medical Equipment and Services 193,064 $3,305,255.68 0.39%
Steris Plc STE G8473T100 Medical Equipment and Services 14,553 $3,250,849.14 0.39%
West Pharmaceutical Services, Inc. WST 955306105 Medical Equipment and Services 13,409 $3,312,291.18 0.39%
The Cooper Companies, Inc. COO 216648501 Medical Equipment and Services 45,015 $3,216,321.75 0.38%
Agilent Technologies, Inc. A 00846U101 Medical Equipment and Services 27,115 $3,063,452.70 0.37%
Thermo Fisher Scientific Inc. TMO 883556102 Medical Equipment and Services 6,367 $3,124,732.59 0.37%
Tempus AI, Inc. (Class A) TEM 88023B103 Pharmaceuticals and Biotechnology 62,481 $2,921,611.56 0.35%
Veeva Systems Inc. (Class A) VEEV 922475108 Health Care Providers 16,528 $2,943,802.08 0.35%
Insulet Corporation PODD 45784P101 Medical Equipment and Services 12,980 $2,803,680.00 0.33%
Boston Scientific Corporation BSX 101137107 Medical Equipment and Services 38,694 $2,700,067.32 0.32%
US Dollar $USD Other 2,245,158 $2,245,157.59 0.27%
Inspire Medical Systems, Inc. INSP 457730109 Medical Equipment and Services 40,003 $2,056,554.23 0.25%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.