First Trust Health Care AlphaDEX® Fund (FXH)
Holdings of the Fund as of 5/22/2026

Total Number of Holdings (excluding cash): 76

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
Organon & Co. OGN 68622V106 Pharmaceuticals and Biotechnology 2,461,992 $33,064,552.56 3.81%
Humana Inc. HUM 444859102 Health Care Providers 106,316 $32,740,012.20 3.77%
Elevance Health Inc. ELV 036752103 Health Care Providers 62,969 $24,853,234.61 2.87%
DaVita Inc. DVA 23918K108 Health Care Providers 119,945 $23,811,481.40 2.75%
Solventum Corporation SOLV 83444M101 Medical Equipment and Services 282,298 $21,688,955.34 2.50%
Exelixis, Inc. EXEL 30161Q104 Pharmaceuticals and Biotechnology 429,802 $21,554,570.30 2.48%
Molina Healthcare, Inc. MOH 60855R100 Health Care Providers 110,632 $20,371,776.48 2.35%
The Cigna Group CI 125523100 Health Care Providers 69,106 $19,780,901.44 2.28%
Biogen Inc. BIIB 09062X103 Pharmaceuticals and Biotechnology 100,552 $19,482,955.52 2.25%
Bio-Rad Laboratories, Inc. (Class A) BIO 090572207 Medical Equipment and Services 66,131 $19,028,533.94 2.19%
Incyte Corporation INCY 45337C102 Pharmaceuticals and Biotechnology 195,859 $19,029,660.44 2.19%
Globus Medical, Inc. (Class A) GMED 379577208 Medical Equipment and Services 213,953 $18,145,353.93 2.09%
Cardinal Health, Inc. CAH 14149Y108 Pharmaceuticals and Biotechnology 87,237 $17,506,721.16 2.02%
Zimmer Biomet Holdings, Inc. ZBH 98956P102 Medical Equipment and Services 203,873 $17,431,141.50 2.01%
Chemed Corporation CHE 16359R103 Health Care Providers 39,040 $17,152,614.40 1.98%
Universal Health Services, Inc. (Class B) UHS 913903100 Health Care Providers 103,002 $16,253,715.60 1.87%
Encompass Health Corporation EHC 29261A100 Health Care Providers 152,458 $16,001,991.68 1.84%
HCA Healthcare, Inc. HCA 40412C101 Health Care Providers 38,953 $15,350,208.71 1.77%
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Pharmaceuticals and Biotechnology 23,859 $15,243,037.92 1.76%
Merck & Co., Inc. MRK 58933Y105 Pharmaceuticals and Biotechnology 122,598 $15,007,221.18 1.73%
Ionis Pharmaceuticals, Inc. IONS 462222100 Pharmaceuticals and Biotechnology 196,394 $14,839,530.64 1.71%
Masimo Corporation MASI 574795100 Medical Equipment and Services 82,911 $14,825,315.91 1.71%
Penumbra, Inc. PEN 70975L107 Medical Equipment and Services 44,912 $14,762,125.28 1.70%
Amgen Inc. AMGN 031162100 Pharmaceuticals and Biotechnology 41,913 $14,221,080.90 1.64%
United Therapeutics Corporation UTHR 91307C102 Pharmaceuticals and Biotechnology 24,869 $14,136,285.67 1.63%
Becton, Dickinson and Company BDX 075887109 Medical Equipment and Services 93,795 $13,846,955.85 1.60%
Pfizer Inc. PFE 717081103 Pharmaceuticals and Biotechnology 525,191 $13,602,446.90 1.57%
Tenet Healthcare Corporation THC 88033G407 Health Care Providers 78,147 $13,580,385.66 1.57%
Illumina, Inc. ILMN 452327109 Pharmaceuticals and Biotechnology 89,734 $12,958,486.94 1.49%
QIAGEN N.V. QGEN N72482156 Medical Equipment and Services 368,316 $12,953,673.73 1.49%
Revvity, Inc. RVTY 714046109 Medical Equipment and Services 126,247 $12,239,646.65 1.41%
Natera, Inc. NTRA 632307104 Medical Equipment and Services 55,306 $11,237,626.14 1.30%
Henry Schein, Inc. HSIC 806407102 Medical Equipment and Services 150,074 $11,136,991.54 1.28%
Quest Diagnostics Incorporated DGX 74834L100 Medical Equipment and Services 56,436 $11,016,871.56 1.27%
Bristol-Myers Squibb Company BMY 110122108 Pharmaceuticals and Biotechnology 182,365 $10,843,422.90 1.25%
Steris Plc STE G8473T100 Medical Equipment and Services 50,019 $10,832,614.83 1.25%
Labcorp Holdings Inc. LH 504922105 Medical Equipment and Services 41,453 $10,774,878.29 1.24%
Gilead Sciences, Inc. GILD 375558103 Pharmaceuticals and Biotechnology 79,360 $10,662,809.60 1.23%
UnitedHealth Group Incorporated UNH 91324P102 Health Care Providers 27,252 $10,586,584.44 1.22%
ResMed Inc. RMD 761152107 Medical Equipment and Services 49,273 $10,251,247.65 1.18%
Certara, Inc. CERT 15687V109 Medical Equipment and Services 1,940,438 $10,167,895.12 1.17%
Medtronic Plc MDT G5960L103 Medical Equipment and Services 127,647 $10,033,054.20 1.16%
GE HealthCare Technologies Inc. GEHC 36266G107 Medical Equipment and Services 155,388 $9,980,571.24 1.15%
The Cooper Companies, Inc. COO 216648501 Medical Equipment and Services 154,694 $9,676,109.70 1.12%
Insmed Incorporated INSM 457669307 Pharmaceuticals and Biotechnology 90,188 $9,581,573.12 1.10%
Neurocrine Biosciences, Inc. NBIX 64125C109 Pharmaceuticals and Biotechnology 55,970 $8,770,499.00 1.01%
Eli Lilly and Company LLY 532457108 Pharmaceuticals and Biotechnology 8,017 $8,538,105.00 0.98%
Sarepta Therapeutics, Inc. SRPT 803607100 Pharmaceuticals and Biotechnology 508,296 $8,539,372.80 0.98%
Waters Corporation WAT 941848103 Medical Equipment and Services 24,760 $8,477,081.22 0.98%
Halozyme Therapeutics, Inc. HALO 40637H109 Pharmaceuticals and Biotechnology 114,089 $7,794,560.48 0.90%
Agilent Technologies, Inc. A 00846U101 Medical Equipment and Services 64,694 $7,437,222.24 0.86%
IQVIA Holdings Inc. IQV 46266C105 Health Care Providers 43,238 $7,259,660.20 0.84%
Align Technology, Inc. ALGN 016255101 Medical Equipment and Services 43,012 $7,037,193.32 0.81%
BioMarin Pharmaceutical Inc. BMRN 09061G101 Pharmaceuticals and Biotechnology 130,532 $7,060,475.88 0.81%
Johnson & Johnson JNJ 478160104 Pharmaceuticals and Biotechnology 30,165 $7,068,866.10 0.81%
Thermo Fisher Scientific Inc. TMO 883556102 Medical Equipment and Services 15,002 $6,725,096.56 0.78%
Medpace Holdings, Inc. MEDP 58506Q109 Pharmaceuticals and Biotechnology 15,355 $6,645,644.00 0.77%
Abbott Laboratories ABT 002824100 Medical Equipment and Services 71,818 $6,277,611.38 0.72%
Medline Inc. (Class A) MDLN 58507V107 Medical Equipment and Services 165,701 $6,132,594.01 0.71%
Zoetis Inc. ZTS 98978V103 Pharmaceuticals and Biotechnology 62,378 $5,072,578.96 0.58%
West Pharmaceutical Services, Inc. WST 955306105 Medical Equipment and Services 13,791 $4,363,748.22 0.50%
DexCom, Inc. DXCM 252131107 Medical Equipment and Services 55,040 $3,968,384.00 0.46%
Royalty Pharma Plc (Class A) RPRX G7709Q104 Pharmaceuticals and Biotechnology 72,054 $3,926,943.00 0.45%
Sotera Health Company SHC 83601L102 Medical Equipment and Services 241,034 $3,774,592.44 0.44%
Edwards Lifesciences Corporation EW 28176E108 Medical Equipment and Services 43,161 $3,702,350.58 0.43%
AbbVie Inc. ABBV 00287Y109 Pharmaceuticals and Biotechnology 15,893 $3,428,120.10 0.40%
IDEXX Laboratories, Inc. IDXX 45168D104 Medical Equipment and Services 6,151 $3,440,684.87 0.40%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Pharmaceuticals and Biotechnology 7,741 $3,363,619.32 0.39%
Intuitive Surgical, Inc. ISRG 46120E602 Medical Equipment and Services 7,497 $3,284,435.70 0.38%
Stryker Corporation SYK 863667101 Medical Equipment and Services 10,518 $3,328,736.64 0.38%
Viking Therapeutics, Inc. VKTX 92686J106 Pharmaceuticals and Biotechnology 106,222 $3,281,197.58 0.38%
Boston Scientific Corporation BSX 101137107 Medical Equipment and Services 55,082 $3,182,637.96 0.37%
Envista Holdings Corporation NVST 29415F104 Medical Equipment and Services 136,241 $3,192,126.63 0.37%
Alnylam Pharmaceuticals, Inc. ALNY 02043Q107 Pharmaceuticals and Biotechnology 10,447 $3,107,460.15 0.36%
Danaher Corporation DHR 235851102 Medical Equipment and Services 18,229 $3,135,388.00 0.36%
Veeva Systems Inc. (Class A) VEEV 922475108 Health Care Providers 19,678 $3,151,825.26 0.36%
US Dollar $USD Other 729,271 $729,271.45 0.08%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.