First Trust Nasdaq Pharmaceuticals ETF (FTXH)
Holdings of the Fund as of 12/17/2025

Total Number of Holdings (excluding cash): 50

Security Name Identifier CUSIP Classification Shares / Quantity Market Value Weighting Descending sort
Johnson & Johnson JNJ 478160104 Pharmaceuticals 6,868 $1,444,546.44 7.41%
Merck & Co., Inc. MRK 58933Y105 Pharmaceuticals 14,466 $1,434,737.88 7.36%
Bristol-Myers Squibb Company BMY 110122108 Pharmaceuticals 25,792 $1,381,161.60 7.08%
AbbVie Inc. ABBV 00287Y109 Pharmaceuticals 5,784 $1,297,409.04 6.65%
Pfizer Inc. PFE 717081103 Pharmaceuticals 49,146 $1,230,615.84 6.31%
Eli Lilly and Company LLY 532457108 Pharmaceuticals 831 $865,727.49 4.44%
Cardinal Health, Inc. CAH 14149Y108 Pharmaceuticals 4,089 $811,421.16 4.16%
Regeneron Pharmaceuticals, Inc. REGN 75886F107 Biotechnology 1,048 $785,779.92 4.03%
Biogen Inc. BIIB 09062X103 Biotechnology 4,518 $777,547.80 3.99%
Vertex Pharmaceuticals Incorporated VRTX 92532F100 Pharmaceuticals 1,556 $699,453.12 3.59%
United Therapeutics Corporation UTHR 91307C102 Pharmaceuticals 1,362 $695,900.28 3.57%
Amgen Inc. AMGN 031162100 Pharmaceuticals 2,115 $689,511.15 3.54%
Viatris Inc. VTRS 92556V106 Pharmaceuticals 57,671 $674,750.70 3.46%
Gilead Sciences, Inc. GILD 375558103 Pharmaceuticals 5,386 $653,644.96 3.35%
Zoetis Inc. ZTS 98978V103 Pharmaceuticals 3,890 $475,552.50 2.44%
Jazz Pharmaceuticals Plc JAZZ G50871105 Pharmaceuticals 2,862 $471,986.74 2.42%
Illumina, Inc. ILMN 452327109 Biotechnology 3,031 $392,696.36 2.01%
PTC Therapeutics, Inc. PTCT 69366J200 Biotechnology 4,347 $325,764.18 1.67%
Incyte Corporation INCY 45337C102 Biotechnology 3,078 $300,505.14 1.54%
Charles River Laboratories International, Inc. CRL 159864107 Biotechnology 1,492 $292,402.16 1.50%
Exelixis, Inc. EXEL 30161Q104 Biotechnology 6,062 $254,604.00 1.31%
Arrowhead Pharmaceuticals, Inc. ARWR 04280A100 Biotechnology 3,760 $243,648.00 1.25%
Medpace Holdings, Inc. MEDP 58506Q109 Biotechnology 406 $226,170.42 1.16%
Elanco Animal Health Incorporated ELAN 28414H103 Pharmaceuticals 9,423 $208,059.84 1.07%
BioMarin Pharmaceutical Inc. BMRN 09061G101 Pharmaceuticals 3,555 $184,149.00 0.94%
Halozyme Therapeutics, Inc. HALO 40637H109 Biotechnology 2,315 $152,257.55 0.78%
Ionis Pharmaceuticals, Inc. IONS 462222100 Pharmaceuticals 1,943 $149,766.44 0.77%
Alkermes Plc ALKS G01767105 Pharmaceuticals 5,140 $144,125.60 0.74%
Amneal Pharmaceuticals, Inc. AMRX 03168L105 Pharmaceuticals 11,357 $140,031.81 0.72%
Neurocrine Biosciences, Inc. NBIX 64125C109 Biotechnology 947 $134,189.90 0.69%
Krystal Biotech, Inc. KRYS 501147102 Biotechnology 561 $132,283.80 0.68%
Protagonist Therapeutics, Inc. PTGX 74366E102 Biotechnology 1,403 $125,344.02 0.64%
Insmed Incorporated INSM 457669307 Biotechnology 609 $120,862.14 0.62%
BridgeBio Pharma, Inc. BBIO 10806X102 Biotechnology 1,600 $118,432.00 0.61%
Guardant Health, Inc. GH 40131M109 Biotechnology 1,228 $119,693.16 0.61%
NewAmsterdam Pharma Company N.V. NAMS N62509109 Biotechnology 3,444 $115,993.92 0.59%
Madrigal Pharmaceuticals, Inc. MDGL 558868105 Biotechnology 189 $103,229.91 0.53%
Catalyst Pharmaceuticals, Inc. CPRX 14888U101 Biotechnology 4,137 $99,288.00 0.51%
Ligand Pharmaceuticals Inc. (Class B) LGND 53220K504 Biotechnology 512 $99,630.08 0.51%
Corcept Therapeutics Inc. CORT 218352102 Pharmaceuticals 1,188 $97,748.64 0.50%
ADMA Biologics, Inc. ADMA 000899104 Biotechnology 4,798 $90,346.34 0.46%
Rhythm Pharmaceuticals, Inc. RYTM 76243J105 Biotechnology 803 $89,823.58 0.46%
Supernus Pharmaceuticals, Inc. SUPN 868459108 Pharmaceuticals 1,836 $89,505.00 0.46%
TG Therapeutics, Inc. TGTX 88322Q108 Biotechnology 2,824 $87,911.12 0.45%
ACADIA Pharmaceuticals Inc. ACAD 004225108 Biotechnology 3,187 $85,825.91 0.44%
Prestige Consumer Healthcare Inc. PBH 74112D101 Pharmaceuticals 1,295 $80,704.40 0.41%
Mirum Pharmaceuticals, Inc. MIRM 604749101 Biotechnology 1,121 $77,349.00 0.40%
Alnylam Pharmaceuticals, Inc. ALNY 02043Q107 Biotechnology 185 $72,538.50 0.37%
Tempus AI, Inc. (Class A) TEM 88023B103 Biotechnology 1,092 $70,559.58 0.36%
Perrigo Company Plc PRGO G97822103 Pharmaceuticals 4,521 $60,400.56 0.31%
US Dollar $USD Other 25,022 $25,021.75 0.13%
Holdings are subject to change.

The holdings information set forth above for the date indicated reflects creation and redemption transactions from the prior business day and may differ from the holdings information currently available from the Fund's custodian and accounting agent. With respect to the market value of the Fund's holdings set forth above, the pricing sources are generally third party vendors. The Fund ultimately relies on pricing information provided by the Fund's accounting agent.